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Merck
모든 사진(4)

주요 문서

R0656

Sigma-Aldrich

Anti-Rab14 (C-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-F protein-binding protein 1, Anti-GTPase Rab14, Anti-RAB14, member RAS oncogene family, Anti-Small GTP binding protein RAB14

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

분자량

antigen ~24 kDa

종 반응성

mouse, human, rat

농도

~1.0 mg/mL

기술

immunoprecipitation (IP): 5-10 μg using whole extract of human Raji cells
indirect immunofluorescence: 2.5-5 μg/mL using rat NRK cells fixed and permeabilized with 4% paraformaldehyde followed by 0.4% saponin
western blot: 1-2 μg/mL using whole extract of mouse brain

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... RAB14(51552)
mouse ... Rab14(68365)
rat ... Rab14(94197)

일반 설명

Rab14 (Ras-related protein) is a Golgi-related Rab, that is located on chromosome 9q33.2. It is present in the endo-lysosomal pathway and contractile vacuole system of membranes. It is expressed almost in all tissues.
Rab14 (Ras-related protein) is a member of the Rab family of small guanosine triphosphatases (GTPases).

애플리케이션

Anti-Rab14 (C-terminal) antibody produced in rabbit has been used in:immunoblotting, immunoprecipitation, indirect immunofluorescence.

생화학적/생리학적 작용

Rab14 (Ras-related protein) participates in membrane trafficking between the Golgi complex and endosomes. It may play an important role in surfactant secretion.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


시험 성적서(COA)

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문서 라이브러리 방문

The functions of Rab GTPases in plant membrane traffic
Woollard AAD and Moore I
Current Opinion in Plant Biology, 11(6), 610-619 (2008)
Annexin A2 interactions with Rab14 in alveolar type II cells
Gou D, et al.
The Journal of Biological Chemistry, 283(19), 13156-13164 (2008)
RabD, a Dictyostelium Rab14-related GTPase, regulates phagocytosis and homotypic phagosome and lysosome fusion
Harris E and Cardelli J
Journal of Cell Science, 115(Pt 18), 3703-3713 (2002)
A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2
Chang M, et al.
PLoS Genetics, 4(6) (2008)
A Lacoma et al.
Virulence, 8(8), 1761-1775 (2017-08-02)
Staphylococcus aureus is a particularly difficult pathogen to eradicate from the respiratory tract. Previous studies have highlighted the intracellular capacity of S.aureus in several phagocytic and non-phagocytic cells. The aim of this study was to define S.aureus interaction within a

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