PZ0129

CP-380736

≥98% (HPLC)

• 동의어(들): 6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one, 6,7-Bis(2-methoxyethoxy)-4(3H)-quinazolinone, PF-00520893
• 실험식(Hill 표기법): C₁₄H₁₈N₂O₅
• CAS Number: 179688-29-0
• Molecular Weight: 294.30
• MDL number: MFCD02678087
• UNSPSC 코드: 51111800
• PubChem Substance ID: 329823716
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: powder
• 색상: off-white to light tan
• solubility: DMSO: ≥10 mg/mL
• 저장 온도: room temp
• SMILES string: COCCOc1cc2N=CNC(=O)c2cc1OCCOC
• InChI: 1S/C14H18N2O5/c1-18-3-5-20-12-7-10-11(15-9-16-14(10)17)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3,(H,15,16,17)
• InChI key: PMQWTUWLIGJTQD-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme.

특징 및 장점

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안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable