추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
predicted mol wt 39-45 kDa
종 반응성
human, rat, mouse
기술
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... ZBP1(81030)
일반 설명
Z-DNA binding protein 1 (ZBP1), also known as interferon (IFN) γ-inducible gene, is a cytoplasmic DNA sensor. It belongs to the family of Z-DNA binding proteins. ZBP1 is majorly expressed in the small intestine and lymphatic tissues. The gene is located on human chromosome 20q13.3.
면역원
a 18 amino acid peptide from near the carboxy-terminus of human ZBP1.
애플리케이션
Anti-ZBP1 antibody produced in rabbit has been used for western blotting.
생화학적/생리학적 작용
Z-DNA binding protein 1 (ZBP1) plays a major role in DNA mediated innate immune responses. It enhances nuclear factor k-light-chain-enhancer of activated B cells (NFκB) activation and proinflammatory cytokine production.
결합
The action of this antibody can be blocked using blocking peptide SBP4401.
물리적 형태
Solution in phosphate buffered saline containing 0.02% sodium azide
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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관련 제품
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Functional roles of pattern recognition receptors that recognize virus nucleic acids in human adipose-derived mesenchymal stem cells
Yu L, et al.
BioMed Research International, 2016 (2016)
ZBP1: innate sensor regulating cell death and inflammation
Kuriakose T and Kanneganti TD
Trends in Immunology, 39(2), 123-134 (2018)
Molecular Lesions of Insulator CTCF and Its Paralogue CTCFL (BORIS) in Cancer: An Analysis from Published Genomic Studies
Voutsadakis I
High Throughput, 7(4), 30-30 (2018)
Lili Yu et al.
BioMed research international, 2016, 9872138-9872138 (2017-01-21)
Human adipose-derived mesenchymal stem cells (hAD-MSCs) are mesenchymal stem cells with the capability to modulate immune responses. Evidence showing that hAD-MSCs could mediate innate immune responses through pattern recognition receptors (PRRs) is increasing. However, the roles of PRRs in regulating
Zhiqiang Zhang et al.
Nature immunology, 14(2), 172-178 (2012-12-12)
DDX41 is a sensor of intracellular double-stranded DNA (dsDNA) in myeloid dendritic cells (mDCs) that triggers a type I interferon response via the signaling adaptor STING. We identified the E3 ligase TRIM21 as a DDX41-interacting protein and found that knockdown
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