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Merck
모든 사진(3)

주요 문서

PLA0105

Sigma-Aldrich

Rabbit anti-XRN1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

동의어(들):

SEP1, strand-exchange protein 1 homolog

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41
종 반응성:
mouse, human
application:
IP
WB
기술:
immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:5,000- 1:15,000
citations:
3

생물학적 소스

rabbit

Quality Level

항체 형태

affinity purified immunoglobulin

항체 생산 유형

primary antibodies

Grade

Powered by Bethyl Laboratories, Inc.

종 반응성

mouse, human

기술

immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:5,000- 1:15,000

수납 번호(accession number)

Q6MZS8

UniProt 수납 번호

배송 상태

wet ice

저장 온도

2-8°C

타겟 번역 후 변형

unmodified

유전자 정보

rabbit ... XRN1(54464)

면역원

The epitope recognized by PLA0105 maps to a region between residue 1650 and the C-terminus (residue 1706) of human 5′-3′ Exoribonuclease 1 using the numbering given in TrEMBL entry Q6MZS8 (GeneID 54464).

물리적 형태

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

기타 정보

5′-3′ exoribonuclease 1 (XRN1) is a ribonuclease localized in the cytoplasm that functions in mRNA metabolism and is found in messenger ribonucleoprotein (mRNP) complexes. The mouse and yeast homologs of XRN1 are Dhm2 and SEP1 respectively. In a glial cell line, XRN1 is induced by glial cell line–derived growth factor (GDNF) and associates with microtubules. XRN1 has also been identified as a candidate tumor suppressor gene in osteogenic sarcoma.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Yang Luo et al.
Biochemistry, 59(43), 4176-4188 (2020-05-05)
Decapping is the first committed step in 5'-to-3' RNA decay, and in the cytoplasm of human cells, multiple decapping enzymes regulate the stabilities of distinct subsets of cellular transcripts. However, the complete set of RNAs regulated by any individual decapping
Jonathan C Reed et al.
Journal of virology, 95(3) (2020-11-06)
Given the projected increase in multidrug-resistant HIV-1, there is an urgent need for development of antiretrovirals that act on virus life cycle stages not targeted by drugs currently in use. Host-targeting compounds are of particular interest because they can offer

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