P7373

PAK7 Active human

≥75% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution

• 동의어(들): PAK5, p21 activated kinase-7
• MDL number: MFCD07371026
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 재조합: expressed in E. coli
• Quality Level: 200
• 분석: ≥75% (SDS-PAGE)
• 양식: buffered aqueous glycerol solution
• 특이 활성도: 10 units/mg protein (Bradford)
• 분자량: protein apparent mol wt ~116 kDa by SDS-PAGE
• UniProt 수납 번호: Q9P286
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... PAK7(57144)

설명

생화학적/생리학적 작용

PAK7 is a PAK family kinase that contains a CDC42/Rac1 interactive binding (CRIB) motif at the N-terminus and a Ste20-like kinase domain at the C-terminus. PAK7 has been implicated in the regulation of cell morphology, motility and transformation. PAK7 is moderately expressed in adult and fetal whole brain and in all specific adult brain regions tested.

단위 정의

One unit will incorporate one nanomole of phosphate into the peptide substrate CKRPRAASFAE per minute at 30 °C and pH 7.2 using a final concentration of 50 μM [32P] ATP.

물리적 형태

Solution in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)