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Merck
모든 사진(2)

Key Documents

P4506

Sigma-Aldrich

Phosphodiesterase I from Crotalus atrox (Western Diamondback Rattlesnake)

Type IV, crude dried venom

동의어(들):

5′-Exonuclease, Oligonucleate 5′-nucleotidohydrolase

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About This Item

효소 위원회 번호:
EC Number:
MDL number:
UNSPSC 코드:
12352204
NACRES:
NA.54

유형

Type IV

Quality Level

형태

crude dried venom

저장 온도

−20°C

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Phosphodiesterase (PDE) is any enzyme that is used to breaks phosphodiester bonds. Phosphodiesterase I, product P4506 from western diamondback rattlesnake, is used in phosphodiesterase activation assays for calmodulin. It is added to hydrolyze AMP. It is a membrane-bound glycoprotein that is used to catalyze the hydrolysis of various nucleotide polyphosphates.
Phosphodiesterase I from Crotalus atrox (Western Diamondback Rattlesnake) has been used to analyse its effect on intracellular calcium concentration of neutrophils. It has also been used in combination with other enzymes to determine the activity of phosphatase enzyme.

생화학적/생리학적 작용

Phosphodiesterase I breaks phosphodiester bonds and catalyzes the hydrolysis of various nucleotide polyphosphates. Phosphodiesterase I is released from eucaryotic plasma membranes by phosphatidylinositol-specific phospholipase C.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

이미 열람한 고객

T Nakabayashi et al.
Journal of biochemistry, 99(3), 703-712 (1986-03-01)
From various rat organs, alkaline phosphodiesterase I was liberated by the action of phosphatidylinositol-specific phospholipase C obtained from Bacillus thuringiensis. Especially, a large amount of alkaline phosphodiesterase I was released from slices of small intestine, testis, lung, and kidney, but
C J Brokaw et al.
The Journal of cell biology, 100(6), 1875-1883 (1985-06-01)
Sea urchin spermatozoa demembranated with Triton X-100 in the presence of EGTA, termed potentially asymmetric, generate asymmetric bending waves in reactivation solutions containing EGTA. After they are converted to the potentially symmetric condition by extraction with Triton and millimolar Ca++
B Fuss et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 17(23), 9095-9103 (1997-12-31)
One of the more complex developmental processes occurring postnatally in the CNS is the formation of the myelin sheath by oligodendrocytes. To examine the molecular events that take place during myelination, we isolated oligodendrocyte-derived cDNA clones, one of which (p421.HB)
Assessment of bioavailable organic phosphorus in tropical forest soils by organic acid extraction and phosphatase hydrolysis
Darch T, et al.
Geoderma, 284, 93-102 (2016)
Identification of Lys49-PLA2 from crude venom of Crotalus atrox as a human neutrophil-calcium modulating protein
Sultan MD, et al.
The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 20(2), 177-183 (2016)

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