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Merck
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Key Documents

P4458

Sigma-Aldrich

Penicillin-Streptomycin

liquid, non-animal origin, suitable for cell culture, BioReagent

동의어(들):

Pen-Strep

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About This Item

UNSPSC 코드:
12352207
NACRES:
NA.76

product name

Penicillin-Streptomycin, Solution Stabilized, with 5,000 units penicillin and 5mg streptomycin/mL, 0.1 μm filtered, BioReagent, suitable for cell culture

Quality Level

무균

0.1 μm filtered

제품 라인

BioReagent

형태

liquid

농도

50 ×

기술

cell culture | mammalian: suitable

불순물

endotoxin, tested

항생제 활성 스펙트럼

Gram-negative bacteria
Gram-positive bacteria

동작 모드

cell wall synthesis | interferes
protein synthesis | interferes

배송 상태

dry ice

저장 온도

−20°C

SMILES string

CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(O)=O.CNC[C@H]4[C@H](O)[C@@H](O)[C@H](CCO)O[C@H]4O[C@H]5[C@@H](O[C@@H](C)C5(O)C=O)O[C@H]6[C@H](O)[C@@H](O)[C@H](NC(N)=N)[C@@H](O)[C@@H]6NC(N)=N

InChI

1S/C23H43N7O12.C16H18N2O4S/c1-7-23(38,6-32)18(42-19-8(5-28-2)12(33)13(34)9(40-19)3-4-31)20(39-7)41-17-11(30-22(26)27)14(35)10(29-21(24)25)15(36)16(17)37;1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9/h6-20,28,31,33-38H,3-5H2,1-2H3,(H4,24,25,29)(H4,26,27,30);3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22)/t7-,8-,9-,10+,11-,12-,13-,14+,15-,16+,17+,18-,19-,20-,23+;11-,12+,14-/m01/s1

InChI key

KMOOCZWLFBSQCW-XFOLRDBHSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Penicillin, a β-lactam antibiotic is extremely active towards bacteria. Penicillins are also termed as penams. It is naturally occurring and has a bicyclic skeleton. Streptomycin is a pseudotrisaccharide. It comprises of a monosubstituted aminocyclitol.

애플리케이션

Penicillin-Streptomycin has been used:
  • as a supplement in Dulbecco′s modified Eagle′s medium (DMEM) to maintain the Huh7 liver hepatoma cell line
  • as a supplement in Roswell park memorial institute-1640 (RPMI) medium to maintain mouse lymphoma YAC-1 cells
  • as a component in minimum essential medium Eagle to treat individual mouse spleens for the preparation of splenocytes
  • as a supplement in FMX-8 complete medium to culture Chinese hamster ovary cells

Recommended for use in cell culture media at 20 ml/L.

생화학적/생리학적 작용

Penicillins can prevent the synthesis of bacterial cell wall. This antibiotic can be used in the treatment of skin and urinary tract infections, upper and lower respiratory infections, and endocarditis. Streptomycin can block Mycobacterium tuberculosis in vitro. Streptomycin inhibits prokaryote protein synthesis by preventing the transition from initiation complex to chain-elongating ribosome, causing miscoding.

성분

This product is formulated to contain 5,000 units penicillin and 5 mg streptomycin/mL solubilized in a proprietary citrate buffer.

기타 정보

20ml,100ml
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Penicillins
xPharm: The Comprehensive Pharmacology Reference (2016)
Streptomyces-derived quorum-sensing systems engineered for adjustable transgene expression in mammalian cells and mice
Weber W, et al.
Nucleic Acids Research, 31(14), e71-e71 (2003)
Aminoglycosides Antibiotics
Comprehensive Medicinal Chemistry II, 7, 629-652 (2007)
Effect of Lactobacillus brevis KB290 on the cell-mediated cytotoxic activity of mouse splenocytes: a DNA microarray analysis
Fukui Y, et al.
The British Journal of Nutrition, 110(9), 1617-1629 (2013)
Jussi Kupari et al.
Cell reports, 27(8), 2508-2523 (2019-05-23)
Sensory functions of the vagus nerve are critical for conscious perceptions and for monitoring visceral functions in the cardio-pulmonary and gastrointestinal systems. Here, we present a comprehensive identification, classification, and validation of the neuron types in the neural crest (jugular)

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