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Merck
모든 사진(2)

주요 문서

P300-05

Sigma-Aldrich

Porcine Coronary Artery Endothelial: PCAEC (Cryovial)

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About This Item

UNSPSC 코드:
41106514
NACRES:
NA.81

생물학적 소스

Porcine coronary artery

Quality Level

양식

solid

포장

pkg of 500,000 cells

제조업체/상표

Cell Applications, Inc

성장 모드

Adherent

핵형

2n = 38

형태학

Endothelial

기술

cell culture | mammalian: suitable

관련 질환(들)

cardiovascular diseases

배송 상태

dry ice

저장 온도

−196°C

일반 설명

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.


Arterial endothelial cells play critical roles in cardiac homeostasis, and insults to the endothelial cells have been linked to a variety of vascular diseases. Porcine artery endothelial cells provide a useful tool to study artery endothelial function and metabolism.PCAEC from Cell Applications, Inc. have been used to investigate a new mechanism of obesity-associated vascular disease by demonstrating that resistin, an adipocyte-derived cytokine implemented in insulin resistance and diabetes, can cause endothelial dysfunction in coronary arteries through oxidative stress and down-regulation of NO synthase (Kougias, 2005). Conversely, secretoneurin was shown to activate expression of NO synthase and calmodulin, leading to endothelial relaxation (Chan, 2011). PCAEC were also used in adhesion and transmigration experiments in a study investigating anti-inflammatory, cardioprotective effects of a novel adenosine-lidocaine drug formulation (Shi, 2012).

세포주 기원

Artery

애플리케이션

cardiovascular function, angiogenesis, vascular biology, regulation of coronary blood flow, cardiac functions, effects of vaso-dilators, coagulation, fibrinolysis, vessel wall tone, cytokine production

성분

Porcine Endothelial Cell Growth Medium that contains 10% FBS and 10% DMSO

제조 메모

  • 2nd passage, >500,000 cells in Porcine Endothelial Cell Growth Medium that contains 10% FBS and 10% DMSO
  • Can be cultured at least 12 doublings

계대배양 정규 작업

Please refer to the PCAEC Culture Protocol.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

문서

Technical information for working with porcine coronary artery endothelial cells including thawing, subculturing and cryopreservation

프로토콜

Technical information for working with porcine coronary artery endothelial cells including thawing, subculturing and cryopreservation.

Technical information for working with porcine coronary artery endothelial cells including thawing, subculturing and cryopreservation.

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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