추천 제품
생물학적 소스
mouse
Quality Level
결합
unconjugated
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
JA9, monoclonal
양식
buffered aqueous solution
종 반응성
human, rat
농도
~1 mg/mL
기술
immunohistochemistry: suitable
indirect ELISA: 1:15,000 using human or rat tissue
western blot: 1:1,000 using human or rat tissue
동형
IgG1
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... ATP2B4(493)
면역원
purified human erythrocyte PMCA.
물리적 형태
Solution in phosphate buffered saline containing 1 mg/ml bovine serum albumin and 0.05 % sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
E Carafoli
Basic research in cardiology, 92 Suppl 1, 59-61 (1997-01-01)
The plasma membrane Ca-pump (134 kDa) is stimulated by calmodulin and by other treatments (exposure to acidic phospholipids, treatments with proteases, phosphorylation by protein kinases A or C, self-association to form oligomers). It is the product of four genes (in
T P Stauffer et al.
The Journal of biological chemistry, 270(20), 12184-12190 (1995-05-19)
Antibodies against the four isoforms of the human plasma membrane Ca(2+)-ATPase (PMCA) were raised using an N-terminal sequence of the pump as epitope. The antibodies against PMCA isoforms 1, 2, and 3 were not species-specific, e.g. they also recognized the
Karolina Varga et al.
Cell calcium, 55(2), 78-92 (2014-01-21)
The expression of the plasma membrane Ca2+ ATPase (PMCA) isoforms is altered in several types of cancer cells suggesting that they are involved in cancer progression. In this study we induced differentiation of MCF-7 breast cancer cells by histone deacetylase
Randa Naffa et al.
Cells, 9(5) (2020-05-18)
Metastatic melanoma is the most aggressive type of skin cancer. Previously, we identified the plasma membrane Ca2+ pump isoform 4b (PMCA4b or ATP2B4) as a putative metastasis suppressor in BRAF mutant melanoma cells. Metastasis suppressors are often downregulated in cancer
Ling Wang et al.
PloS one, 10(4), e0122932-e0122932 (2015-04-24)
An increased risk for developing essential hypertension, stroke and diabetes is associated with single nucleotide gene polymorphisms in renalase, a newly described secreted flavoprotein with oxidoreductase activity. Gene deletion causes hypertension, and aggravates acute ischemic kidney (AKI) and cardiac injury.
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