추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
IgG fraction of antiserum
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
분자량
antigen ~25 kDa
종 반응성
human
기술
microarray: suitable
western blot: 1:4,000-1:8,000 using HeLa cell mitochondria extracts
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... PRDX3(10935)
일반 설명
PRDX3, also known as antioxidant protein 1 (AOP1), MER-5, or SP-22, belongs to a family of proteins termed peroxiredoxins (Prx). It is a mitochondrial protein.
The PRDX3 gene is located on the human chromosome at 10q26.11.
특이성
Whole antiserum is purified to provide an IgG fraction of antiserum Anti-Peroxiredoxin 3 recognizes human PRDX3.
면역원
synthetic peptide corresponding to amino acids 241-256 of human peroxiredoxin 3, conjugated to KLH via an N-terminal lysine residue.
애플리케이션
Anti-Peroxiredoxin 3 antibody produced in rabbit has been used in western blotting.
생화학적/생리학적 작용
Peroxiredoxin 3 (PRDX3) catalyzes the reduction of peroxides in the presence of thioredoxin. The Prx family has been identified in association with a variety of diverse cellular functions including growth control, proliferation, differentiation, and in the response to oxidative stress. PRDX3 is required to maintain normal mitochondrial function through direct activation by c-Myc, which may explain its overexpression during neoplastic transformation.
물리적 형태
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
저장 및 안정성
For continuous use, store at 2-8 °C for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in frost-free freezers,is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
적합한 제품을 찾을 수 없으신가요?
당사의 제품 선택기 도구.을(를) 시도해 보세요.
Storage Class Code
11 - Combustible Solids
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Peroxiredoxin III, a mitochondrion-specific peroxidase, regulates apoptotic signaling by mitochondria
Chang TM, et al.
The Journal of Biological Chemistry, 279(40), 41975-41984 (2004)
Afsane Bahrami et al.
Journal of cellular physiology, 233(3), 1929-1939 (2017-05-26)
Cervical cancer (CC) is the third most common malignancy in women globally, and persistent infection with the oncogenic human papillomaviruses (HPV) is recognized as the major risk factor. The pathogenesis of CC relies on the interplay between the tumorigenic properties
J G van Andel
Radiologia clinica, 46(1), 50-69 (1977-01-01)
80 patients with carcinoma of the nasopharynx classified according to TNM categories who have been treated in the RRTI between January 1947 and January 1966 are discussed. During 1947-1957 patients were treated by orthovoltage, and after this period by cobalt
Peroxiredoxin 3 levels regulate a mitochondrial redox setpoint in malignant mesothelioma cells
Cunniff B, et al.
Redox Biology, 3(40), 79-87 (2014)
Pauline J van der Watt et al.
Molecular cancer therapeutics, 15(4), 560-573 (2016-02-03)
Karyopherin beta 1 (Kpnβ1) is a nuclear transport receptor that imports cargoes into the nucleus. Recently, elevated Kpnβ1 expression was found in certain cancers and Kpnβ1 silencing with siRNA was shown to induce cancer cell death. This study aimed to
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.