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Merck
모든 사진(1)

Key Documents

N6756

Sigma-Aldrich

Nicotinamide hypoxanthine dinucleotide, reduced form, sodium salt

Grade I, ≥95%

동의어(들):

Deamino DPNH, Deamino NADH, Deaminodiphosphopyridine nucleotide, reduced form

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About This Item

실험식(Hill 표기법):
C21H28N6O15P2 · xNa+
Molecular Weight:
666.43 (free acid basis)
MDL number:
UNSPSC 코드:
41106305
PubChem Substance ID:
NACRES:
NA.51

유형

Grade I

Quality Level

분석

≥95%

형태

powder

저장 온도

−20°C

SMILES string

NC(=O)C1=CN(C=CC1)C2OC(COP(O)(=O)OP(O)(=O)OCC3OC(C(O)C3O)n4cnc5C(=O)N=CNc45)C(O)C2O

InChI

1S/C21H28N6O15P2/c22-17(32)9-2-1-3-26(4-9)20-15(30)13(28)10(40-20)5-38-43(34,35)42-44(36,37)39-6-11-14(29)16(31)21(41-11)27-8-25-12-18(27)23-7-24-19(12)33/h1,3-4,7-8,10-11,13-16,20-21,28-31H,2,5-6H2,(H2,22,32)(H,34,35)(H,36,37)(H,23,24,33)

InChI key

WXWNHSQIXJHVJY-UHFFFAOYSA-N

애플리케이션

Nicotinamide hypoxanthine dinucleotide, reduced (deamino-NADH) may be used study the specificity and kinetics of NADH: ubiquinone oxidoreductase(s).

기타 정보

Analog of β-NADH

제조 메모

Enzymatically reduced.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

Jiwon Kang et al.
Journal of biochemistry and molecular biology, 40(1), 53-57 (2007-01-25)
The enzymatic properties of NADH:quinone oxidoreductase were examined in Triton X-100 extracts of Bacillus cereus membranes by using the artificial electron acceptors ubiquinone-1 and menadione. Membranes were prepared from B. cereus KCTC 3674 grown aerobically on a complex medium and
Kenji Kawahara et al.
Journal of biochemistry, 145(2), 229-237 (2008-12-09)
In the intraerythrocytic stages of malaria parasites, mitochondria lack obvious cristae and are assumed to derive energy through glycolysis. For understanding of parasite energy metabolism in mammalian hosts, we isolated rodent malaria mitochondria from Plasmodium yoelii yoelii grown in mice.
Jukka Pätsi et al.
The Biochemical journal, 409(1), 129-137 (2007-09-27)
LHON (Leber hereditary optic neuropathy) is a maternally inherited disease that leads to sudden loss of central vision at a young age. There are three common primary LHON mutations, occurring at positions 3460, 11778 and 14484 in the human mtDNA
Rosa Pello et al.
Human molecular genetics, 17(24), 4001-4011 (2008-09-23)
Leber's hereditary optic neuropathy (LHON), the most frequent mitochondrial disorder, is mostly due to three mitochondrial DNA (mtDNA) mutations in respiratory chain complex I subunit genes: 3460/ND1, 11778/ND4 and 14484/ND6. Despite considerable clinical evidences, a genetic modifying role of the
Pilvi Maliniemi et al.
Mitochondrion, 9(6), 394-401 (2009-07-21)
Seven of the 45 subunits of mitochondrial NADH:ubiquinone oxidoreductase (complex I) are mitochondrially encoded and have been shown to harbor pathogenic mutations. We modeled the human disease-associated mutations A4136G/ND1-Y277C, T4160C/ND1-L285P and C4171A/ND1-L289M in a highly conserved region of the fourth

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