MSQC8

SigmaMAb Antibody Drug Conjugate (ADC) Mimic

Antibody Cysteine-Fluorophore Conjugate Standard

• 동의어(들): Antibody Drug Conjugate
• UNSPSC 코드: 12352204
• NACRES: NA.32

속성

• 재조합: expressed in CHO cells
• Quality Level: 200
• 항체 생산 유형: primary antibodies
• 양식: lyophilized powder
• 배송 상태: wet ice
• 저장 온도: −20°C

설명

일반 설명

SigmaMab Antibody Drug Conjugate (ADC) Mimic, is a non-toxic drug mimic that is utilized as a standard for mass spectrometry and high performance liquid chromatography. The ADC Mimic conjugates SigmaMab (MSQC4), an IgG1 monoclonal antibody, to dansyl fluorophores via an LC-SMCC crosslinker. This dansyl-LC-SMCC attachment serves as the substitution for the toxic payload of a real ADC.

The ADC Mimic allows for safer and more consistent testing, making it the optimal product over real ADCs. It is also a more affordable product compared to real ADCs. With the help of this non-toxic product, LC-MS processes can be developed in a safer environment.

애플리케이션

Poster: Antibody Drug Conjugate Mimic Enables LC-MS Method Development Without Risk

Poster: LC-UV-MS Method Development for Antibody Drug Conjugates Using a Non-Toxic ADC-Mimic

Poster: LC-MS Method Development for Antibody Drug Conjugates Using a Non-Toxic ADC Mimic

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3