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Merck
모든 사진(1)

Key Documents

추가 자료

M3808

Sigma-Aldrich

MRS 2179 ammonium salt hydrate

≥98% (HPLC)

동의어(들):

2′-Deoxy-N6-methyl adenosine 3′,5′-diphosphate diammonium salt

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C11H17N5O9P2 · xNH3 · yH2O
CAS Number:
101204-49-3
Molecular Weight:
425.23 (anhydrous free acid basis)
UNSPSC 코드:
12352200
PubChem Substance ID:
24278551
NACRES:
NA.77

Quality Level

100

분석

≥98% (HPLC)

저장 조건

desiccated

solubility

DMSO: 1.1 mg/mL
H2O: >10 mg/mL

배송 상태

wet ice

저장 온도

−20°C

SMILES string

N.O.CNc1ncnc2n(cnc12)[C@H]3C[C@H](OP(O)(O)=O)[C@@H](COP(O)(O)=O)O3

InChI

1S/C11H17N5O9P2.H3N.H2O/c1-12-10-9-11(14-4-13-10)16(5-15-9)8-2-6(25-27(20,21)22)7(24-8)3-23-26(17,18)19;;/h4-8H,2-3H2,1H3,(H,12,13,14)(H2,17,18,19)(H2,20,21,22);1H3;1H2/t6-,7+,8+;;/m0../s1

InChI key

DEQIORFOBOEGKZ-ZJWYQBPBSA-N

유전자 정보

human ... P2RY1(5028)

애플리케이션

MRS 2179 ammonium salt hydrate has been used as a P2Y1 receptor antagonist in porcine coronary small arteries, endothelial cells, and hippocampal astrocytes.

생화학적/생리학적 작용

MRS 2179 resists localized venous thrombosis and is useful in treating thrombotic syndromes due to its platelet aggregation inhibition functionality.
Competitive P2Y1 purinoceptor antagonist.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

시험 성적서(COA)

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Adenosine 5′-diphosphate sodium salt bacterial, ≥95% (HPLC)

Sigma-Aldrich

A2754

Adenosine 5′-diphosphate sodium salt

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European journal of pharmacology, 412(3), 213-221 (2001-02-13)
The effects of a potent P2Y1 receptor antagonist, N6-methyl-2'-deoxyadenosine-3',5'-bisphosphate (MRS2179) on adenosine-5'-diphosphate (ADP)-induced platelet aggregation in vitro, ex vivo and on the bleeding time in vivo were determined. In suspensions of washed platelets, MRS2179 inhibited ADP-induced platelet shape change, aggregation
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