M0398

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone

elastase inhibitor, powder, ≥98% (TLC)

• 동의어(들): N-(Methoxysuccinyl)-L-alanyl-L-alanyl-L-prolyl-L-valine chloromethylketone
• 실험식(Hill 표기법): C₂₂H₃₅ClN₄O₇
• CAS Number: 65144-34-5
• Molecular Weight: 502.99
• Beilstein: 6167019
• MDL number: MFCD00077136
• UNSPSC 코드: 12352202
• PubChem Substance ID: 24896552
• NACRES: NA.77

속성

• 제품명: N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone, elastase inhibitor
• 분석: ≥98% (TLC)
• 양식: powder
• mp: 159 °C
• solubility: methanol: 50 mg/mL, clear, colorless
• 저장 온도: −20°C
• SMILES string: COC(=O)CCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)CCl
• InChI: 1S/C22H35ClN4O7/c1-12(2)19(16(28)11-23)26-21(32)15-7-6-10-27(15)22(33)14(4)25-20(31)13(3)24-17(29)8-9-18(30)34-5/h12-15,19H,6-11H2,1-5H3,(H,24,29)(H,25,31)(H,26,32)/t13-,14-,15-,19-/m0/s1
• InChI key: PJGDFLJMBAYGGC-XLPNERPQSA-N

설명

일반 설명

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is a tetrapeptide, cell-permeable and non-cytotoxic inhibitor.

애플리케이션

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone has been used as an elastase specific inhibitor.

생화학적/생리학적 작용

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone acts as a competitive inhibitor of human leukocyte elastase (HLE).

Irreversible inhibitor of human leukocyte and neutrophil elastase.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)