추천 제품
생물학적 소스
goat
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
lyophilized powder
종 반응성
human
기술
flow cytometry: 2.5 μg using 106 cells
western blot: 0.1-0.2 μg/mL
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
human ... LTBR(4055)
일반 설명
The antibody will recognize recombinant human LT-βR. Applications include in immunoblotting, flow cytometry, and agonist activity.
면역원
recombinant human lymphotoxin β receptor extracellular domain expressed in NS0 cells.
생화학적/생리학적 작용
Lymphotoxins (LT) alpha and beta are homologs of tumor necrosis factor. These cytokines play important role in the development and function of immune system, immune response and autoimmunity. The signaling mediated by LTβ receptor mediates autoimmune reactions and the development of secondary lymphoid organs.
물리적 형태
Lyophilized from 0.2 μm filtered solution of phosphate buffered saline containing carbohydrates.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Hugh McDevitt et al.
Arthritis research, 4 Suppl 3, S141-S152 (2002-07-12)
Tumor necrosis factor (TNF)-alpha and lymphotoxin (LT) alpha/beta play multiple roles in the development and function of the immune system. This article focuses on three important aspects of the effects of these cytokines on the immune response and on autoimmunity.
Role of lymphotoxin in experimental models of infectious diseases: potential benefits and risks of a therapeutic inhibition of the lymphotoxin-beta receptor pathway.
Thomas W Spahn et al.
Infection and immunity, 73(11), 7077-7088 (2005-10-22)
H Körner et al.
Immunology and cell biology, 74(5), 465-472 (1996-10-01)
Tumour necrosis factor (TNF) is a highly potent, proinflammatory cytokine with broad-ranging functions from the regulation of endothelial cell adhesion molecules to facilitate entry of leucocytes into tissues, to direct induction of cellular cytotoxicity. This diversity of function potentially attributable
Yu Mikami et al.
PloS one, 9(12), e114791-e114791 (2014-12-17)
Asthma-related mortality has been decreasing due to inhaled corticosteroid use, but severe asthma remains a major clinical problem. One characteristic of severe asthma is resistance to steroid therapy, which is related to neutrophilic inflammation. Recently, the tumor necrosis factor superfamily
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