추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
fractionated antiserum
항체 생산 유형
primary antibodies
클론
polyclonal
양식
lyophilized powder
종 반응성
human
포장
vial of 2 mL lyophilized antiserum
기술
direct ELISA: 1:10,000 using using human lactoferrin
UniProt 수납 번호
저장 온도
2-8°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... LTF(4057)
일반 설명
Lactoferrin, globular glycoprotein belongs to transferrin protein family. It is mapped to human chromosome 3p21.31. Lactoferrin comprises 692 amino acids with two globular lobes linked by α-helix and belongs to transferrin family. It exists in three isoforms namely lactoferrin-α, lactoferrin-γ, and lactoferrin-β. Lactoferrin corresponds to a molecular weight of 80 kDa.
특이성
Rabbit polyclonal anti-lactoferrin antibody reacts with purified lactoferrin and human milk, but does not react with human serum proteins.
애플리케이션
Anti-Lactoferrin antibody produced in rabbit has been used in:
- western blotting
- indirect immunofluorescence
- flow cytometry
- enzyme-linked immunosorbent assay (ELISA)
생화학적/생리학적 작용
A primary function of lactoferrin is to bind and transport iron ions. However, lactoferrin is also an effective antibacterial, antiviral, antiparasitic, catalytic (RNA degrading), anti-cancer molecule. It elicits anti-inflammatory effects in asthma. It has immunomodulatory and anti-inflammatory functionality and is a potential protein nutraceutical.
물리적 형태
Lyophilized from 0.01 M phosphate buffered saline, pH 7.2
재구성
Reconstitute with 2 ml deionized water.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
Alan Grupioni Lourenço et al.
World journal of virology, 3(2), 11-17 (2014-07-16)
To study the effect of seminal plasma on Chemokine (C-C motif) ligand 20 (CCL20) production by epithelial cells and its relationship with lactoferrin. HEC-1A cells, a cell line derived from a monostratified endocervical epithelium, were incubated with samples of seminal
A novel murine anti-lactoferrin monoclonal antibody activates human polymorphonuclear leukocytes through membrane-bound lactoferrin and TLR4
Hu XM, et al.
BioMed Research International, 2015(2), 439-439 (2015)
Pamela L Beatty et al.
Cancer prevention research (Philadelphia, Pa.), 3(4), 438-446 (2010-03-25)
Association of chronic inflammation with an increased risk of cancer is well established, but the contributions of innate versus adaptive immunity are not fully delineated. There has furthermore been little consideration of the role played by chronic inflammation-associated antigens, including
Lulu Hu et al.
Scientific reports, 7(1), 4230-4230 (2017-06-28)
Lactoferrin (LTF), an important first line defense molecule against infection, is a common target for humoral autoimmune reactions in humans. Since LTF is a multifunctional protein capable of activating innate immune cells via various surface receptors, we hypothesized that LTF-containing
Expression, purification, and breast cancer cell inhibiting effect of recombinant human lactoferrin C-lobe
Hu L, et al.
Bioscience, Biotechnology, and Biochemistry, 80(2), 257-263 (2016)
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