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Merck
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Key Documents

L1645

Sigma-Aldrich

Anti-Human Lambda Light Chain (Bound and Free) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.46

생물학적 소스

goat

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

secondary antibodies

클론

polyclonal

형태

buffered aqueous solution

기술

indirect ELISA: 1:2,500

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

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관련 카테고리

일반 설명

Immunoglobulins (Ig) are produced by the B cells and play crucial role in host humoral immune response. A typical immunoglobulin consists of two heavy chains and two light chains. The two light chains are either κ or the λ chain. The B cells express one type of light chain during their life time.
Lambda (λ) light chain comprises an amino-terminal variable region and carboxy-terminal constant region. λ chain is biologically critical and constitutes up to 30 to 40% of human immunoglobulin (Ig) molecules. The human λ locus is mapped to the chromosome location 22.

애플리케이션

Anti-Human Lambda Light Chain (Bound and Free) antibody has been used in surface plasmon resonance assay.
Anti-Human Lambda Light Chain (bound and free) antibody produced in goat has been used in indirect enzyme linked immuno sorbent assay (ELISA).

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative

저장 및 안정성

For continuous use, store at 2-8 °C for up to one month.For extended storage, solution may be frozen inworking aliquots. Repeated freezing and thawing is notrecommended. Storage in "frost-free" freezers is notrecommended.If slight turbidity occurs upon prolonged storage, clarify by centrifugation before use.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

An anti-TL1A antibody for the treatment of asthma and inflammatory bowel disease
MAbs, 10(4), 664-677 (2018)
Structural and functional properties of human lambda-light-chain variable-region subgroups.
A Solomon et al.
Clinical and diagnostic laboratory immunology, 2(4), 387-394 (1995-07-01)
Adam W Clarke et al.
mAbs, 10(4), 664-677 (2018-02-14)
TL1A is an attractive therapeutic target for the treatment of mucosal inflammation associated with inflammatory bowel disease (IBD) and asthma. Blockade of the TL1A pathway has been shown to reduce inflammatory responses while leaving baseline immunity intact, and to be
Jerry A Katzmann et al.
Clinical chemistry, 48(9), 1437-1444 (2002-08-27)
The detection of monoclonal free light chains (FLCs) is an important diagnostic aid for a variety of monoclonal gammopathies and is especially important in light-chain diseases, such as light-chain myeloma, primary systemic amyloidosis, and light-chain-deposition disease. These diseases are more

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