K3250
Kynuramine dihydrobromide
monoamine oxidase substrate, fluorogenic, ≥97% (TLC), crystalline
동의어(들):
3-(2-Aminophenyl)-3-oxopropanamine
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모든 사진(4)
About This Item
실험식(Hill 표기법):
C9H12N2O · 2HBr
CAS Number:
Molecular Weight:
326.03
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.32
추천 제품
제품명
Kynuramine dihydrobromide, crystalline
분석
≥97% (TLC)
Quality Level
양식
crystalline
solubility
water: 50 mg/mL, clear to slightly hazy
저장 온도
−20°C
SMILES string
Br.NCCC(=O)c1ccccc1N
InChI
1S/C9H12N2O.BrH/c10-6-5-9(12)7-3-1-2-4-8(7)11;/h1-4H,5-6,10-11H2;1H
InChI key
YUPVVZSYBUIDQR-UHFFFAOYSA-N
애플리케이션
Kynuramine dihydrobromide has been used as a substrate for monoamine oxidase.
생화학적/생리학적 작용
Kynuramine dihydrobromide is a substrate for the enzyme monoamine oxidase. The end product is the formation of fluorescence detectable 4-hydroxyquinoline (4-HOQ) measured in a fluorescence spectrophotometer at 380 nm.
기질
Substrate for monoamine oxidase
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
Evidence for the involvement of the noradrenergic system, dopaminergic and imidazoline receptors in the antidepressant-like effect of tramadol in mice
Jesse CR, et al.
Pharmacology, Biochemistry, and Behavior, 95(3), 344-350 (2010)
Zhanna V Chirkova et al.
Drug development research, 79(2), 81-93 (2018-03-24)
Hit, Lead & Candidate Discovery In recent studies, we have shown that pyrrolo[3,4-f]indole-5,7-dione and indole-5,6-dicarbonitrile derivatives act as good potency in vitro inhibitors of the monoamine oxidase (MAO) enzymes. To expand on these series and to further derive structure-activity relationships
Chronic dietary mercury exposure causes oxidative stress, brain lesions, and altered behaviour in Atlantic salmon (Salmo salar) parr
Berntssen MHG, et al.
Aquatic Toxicology (Amsterdam, Netherlands), 65(1), 55-72 (2003)
Magdalena S Nel et al.
Bioorganic chemistry, 69, 20-28 (2016-09-24)
In the present study a series of fifteen 2-heteroarylidene-1-indanone derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) A and B. These compounds are structurally related to series of heterocyclic chalcone derivatives which have previously been
Synergistic antidepressant-like effect of ferulic acid in combination with piperine: involvement of monoaminergic system
Li G, et al.
Metabolic Brain Disease, 30(6), 1505-1514 (2015)
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