H2539

Anti-HAP40 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 동의어(들): Anti-Huntingtin-associated Protein 40kDa
• MDL number: MFCD03791872
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen ~40 kDa
• 종 반응성: mouse
• 기술: western blot: 1:500-1:1,000 using mouse brain
• UniProt 수납 번호: Q00558
• 배송 상태: dry ice
• 저장 온도: −20°C
• 유전자 정보: mouse ... F8A1(14070)

설명

일반 설명

Three sequence-identical paralogs of the factor VIII intronic transcript A (F8A) gene codes for huntingtin-associated protein 40 (HAP40) in humans. In amniotes, HAP40 is coded by a single-exon gene (SEG). The F8A or coagulation factor VIII-associated 1 (F8A1) gene is located on human chromosome Xq28.

면역원

peptide corresponding to the mouse HAP40 protein (amino acids 314-325).

애플리케이션

Co-immunoprecipitates Huntingtin protein.

생화학적/생리학적 작용

Huntingtin-associated protein 40 (HAP40) acts as an effector of Ras-related protein 5 (Rab5) It interacts with huntingtin (HTT). HAP40 may participate in the abnormal nuclear localization of mutant huntingtin identified in Huntington′s disease degenerating neurons.

표적 설명

HAP40 is a 40 kDa Huntingtin-associated protein. It islikely to contribute to the function of normal huntintinand is a candidate for involvement in the aberrantnuclear localization of mutant huntingtin found indegenerating neurons in Huntington′s

물리적 형태

Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable