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Merck
모든 사진(1)

Key Documents

GW21442

Sigma-Aldrich

Anti-DPP4 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-CD26, Anti-Dipeptidyl peptidase 4

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

chicken

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

종 반응성

rat, mouse, human

제조업체/상표

Genway 15-288-21442

기술

immunocytochemistry: suitable
western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... DPP4(1803)

일반 설명

Dipeptidyl peptidase-4 (DPP4) is a serine type protease is also known as CD26 or adenosine deaminase binding protein. It is expressed in the plasma membranes of T cells and activated natural killer or B cells. Its expressions also have been found on a number of endothelial and differentiated epithelial cells.

면역원

Immunogen Sequence: GI # 4503367, sequence 547-610
Recombinant dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)

애플리케이션

Anti-DPP4 antibody produced in chicken is suitable for immunocytochemistry and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

생화학적/생리학적 작용

Dipeptidyl peptidase-4 (DPP4) is a protein encoded by the DPP4 gene in humans. The T cell activation molecule DPP4 is associated with a 43kDa protein. It is associated with multiple sclerosis (MS) pathophysiology. DPP4 interacts on the T cell surface along with adenosine deaminase (ADA). Mutation in DPP4 causes an X-linked Simpson-Golabi-Behmel syndrome.

물리적 형태

Solution in phosphate buffered saline containing 0.02% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


시험 성적서(COA)

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문서 라이브러리 방문

C Durinx et al.
European journal of biochemistry, 267(17), 5608-5613 (2000-08-22)
Dipeptidyl peptidase IV (DPPIV, EC 3.4.14.5) is a serine type protease with an important modulatory activity on a number of chemokines, neuropeptides and peptide hormones. It is also known as CD26 or adenosine deaminase (ADA; EC 3.5.4.4) binding protein. DPPIV
J Kameoka et al.
Science (New York, N.Y.), 261(5120), 466-469 (1993-07-23)
CD26, the T cell activation molecule dipeptidyl peptidase IV (DPPIV), associates with a 43-kilodalton protein. Amino acid sequence analysis and immunoprecipitation studies demonstrated that this 43-kilodalton protein was adenosine deaminase (ADA). ADA was coexpressed with CD26 on the Jurkat T
Jamshid Davoodi et al.
Proteomics, 7(13), 2300-2310 (2007-06-06)
Simpson-Golabi-Behmel syndrome (SGBS) is an X-linked condition shown to be the result of deletions of the glypican-3 (GPC3) gene. GPC3 is a proteoglycan localized to the cell membrane via a glycosylphosphatidyl-inositol (GPI) anchor. To further elucidate the GPC3 function(s), we
Marta Tejera-Alhambra et al.
Clinical immunology (Orlando, Fla.), 150(2), 170-183 (2014-01-15)
Multiple sclerosis (MS) is a prototypic Th1/Th17 chronic autoimmune disease of the central nervous system. Dipeptidyl peptidase 4 (DPP4 or CD26) is a multifunctional molecule involved in autoimmune diseases' pathophysiology. We sought to integrate disparate pieces of data and analyze
Cuiqing Ma et al.
Vaccine, 32(46), 6170-6176 (2014-09-23)
The newly emerged Middle East respiratory syndrome coronavirus (MERS-CoV) is currently spreading among humans, making development of effective MERS vaccines a high priority. A defined receptor-binding domain (RBD) in MERS-CoV spike protein can potentially serve as a subunit vaccine candidate

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