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Merck
모든 사진(1)

주요 문서

GW21017

Sigma-Aldrich

Anti-Tenascin antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-Cytotactin, Anti-Neuronectin, Anti-Tenascin C (hexabrachion)

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

chicken

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

종 반응성

human

제조업체/상표

Genway 15-288-21017

기술

western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... TNC(3371)

면역원

Immunogen Sequence: GI # 4504549, sequence 18-175
Recombinant tenascin C (hexabrachion)

애플리케이션

Anti-Tenascin antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. It is also used for immunohistology.

생화학적/생리학적 작용

Tenascin-C (TNC) is an extracellular matrix protein that is expressed at low levels in normal adult tissue but is highly expressed around many tumors including ovarian tumors. High levels are observed in many diseases like heart failure, thrombosis, atherosclerosis and cancer. It plays an indispensable role in tumor development. Expression of this gene is induced by growth factors as well as mechanical strain in fibroblast. It is up-regulated within glioma tissues and cultured glioma cell lines. TNC possesses a multi-modular structure with a variety of functional properties.

물리적 형태

Solution in phosphate buffered saline containing 0.02% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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문서 라이브러리 방문

Yucal Wang et al.
Oncology research, 20(11), 509-516 (2013-09-26)
Osteosarcoma (OS) is a kind of malignancy wherein the tumor cells form malignant bone-like or bone tissue. Tenascin-C (TN-C), an important extracellular matrix (ECM) protein, plays an indispensable role in tumor development. However, its regulatory factors, expression, and function in
Nicole Brösicke et al.
Cell and tissue research, 354(2), 409-430 (2013-08-22)
The extracellular matrix (ECM) protein tenascin-C (TN-C) is upregulated within glioma tissues and cultured glioma cell lines. TN-C possesses a multi-modular structure and a variety of functional properties have been reported for its domains. We describe five novel monoclonal antibodies
D Tastekin et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(7), 6619-6625 (2014-04-04)
Tenascin-C (TNC) is a key molecule in tissue remodeling, and high levels are observed in many diseases, including heart failure, thrombosis, atherosclerosis, and cancer. High TNC expression by immunohistochemical analysis has been shown in invasive and metastasizing tissues from a
Tastekin Didem et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(7), 6777-6782 (2014-04-12)
Tenascin-C (TNC) is an extracellular matrix protein that is expressed at low levels in normal adult tissue but is highly expressed around many tumors including ovarian tumors. The objective of this study was to determine the clinical significance of the
Daniel J Gibson et al.
Investigative ophthalmology & visual science, 54(7), 4776-4781 (2013-06-27)
To determine the topographical location and time course of development of corneal haze in a phototherapeutic keratectomy model using slit lamp examination, macrophotography, quantitative image analysis, and immunofluorescence staining of corneal sections. Rabbit corneas were ablated with an excimer laser

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