추천 제품
생물학적 소스
chicken
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
종 반응성
rat, human, mouse
제조업체/상표
Genway 15-288-20056A
기술
western blot: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... TFE3(7030)
면역원
Immunogen Sequence: GI # 8659574, sequence 432-541
Recombinant transcription factor binding to IGHM enhancer 3
애플리케이션
Anti-Transcription Factor E3 antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200.
생화학적/생리학적 작용
TFE3 (Transcription factor E3) gene encodes a helix-loop-helix transcription factor that contains a helix-loop-helix domain and binds to MUE3-type E-box sequences (5′-CANNTG-3′). It plays a key role in transforming growth factor β (TGF-β) induced activation of the plasminogen activator inhibitor-1 (PAI-1) promoter. Chromosomal translocation resulting in the fusion of TFE3 gene to a novel gene, designated PRCC, is observed in papillary renal cell carcinomas. A chromosomal aberration in TFE3 is observed in patients with alveolar soft part sarcoma.
물리적 형태
Solution in phosphate buffered saline containing 0.02% sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
적합한 제품을 찾을 수 없으신가요?
당사의 제품 선택기 도구.을(를) 시도해 보세요.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
H Beckmann et al.
Genes & development, 4(2), 167-179 (1990-02-01)
The muE3 motif within the immunoglobulin heavy-chain enhancer is required for full enhancer activity and is known to bind one, or perhaps a family, of related ubiquitous nuclear proteins. Here, we present the isolation of a cDNA that encodes an
P Argani et al.
The American journal of pathology, 159(1), 179-192 (2001-07-05)
The unbalanced translocation, der(17)t(X;17)(p11.2;q25), is characteristic of alveolar soft part sarcoma (ASPS). We have recently shown that this translocation fuses the TFE3 transcription factor gene at Xp11.2 to ASPL, a novel gene at 17q25. We describe herein eight morphologically distinctive
M A Weterman et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(26), 15294-15298 (1996-12-24)
The (X;1)(p11;q21) translocation is a recurrent chromosomal abnormality in a subset of human papillary renal cell carcinomas, and is sometimes the sole cytogenetic abnormality present. Via positional cloning, we were able to identify the genes involved. The translocation results in
X Hua et al.
Genes & development, 12(19), 3084-3095 (1998-10-09)
Members of the TGF-beta superfamily influence a broad range of biological activities including stimulation of wound healing and inhibition of cell growth. TGF-beta signals through type I and II receptor serine/ threonine kinases and induces transcription of many genes including
J Clark et al.
Oncogene, 15(18), 2233-2239 (1997-12-11)
We demonstrate that the cytogenetically defined translocation t(X;1)(p11.2;p34) observed in papillary renal cell carcinomas results in the fusion of the splicing factor gene PSF located at 1p34 to the TFE3 helix-loop-helix transcription factor gene at Xp11.2. In addition we define
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.