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Merck
모든 사진(1)

Key Documents

GW20030F

Sigma-Aldrich

Anti-β-2-Microglobulin antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-B2MG

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

chicken

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

종 반응성

human

제조업체/상표

Genway 15-288-20030F

기술

western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... B2M(567)

면역원

β-2-Microglobulin native protein.
Immunogen Sequence: GI # 4757826, sequence 1-119

애플리케이션

Anti-β-2-Microglobulin antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200.

생화학적/생리학적 작용

β-2-Microglobulin is a serum protein that forms a non-covalent association with the heavy chain of the major histocompatibility complex (MHC) class I, which is involved in the presentation of peptide antigens to the immune system. Defects in this gene can cause hypercatabolic hypoproteinemia. Amyloidosis is caused upon polymerization of intact β 2-microglobulin in patients on chronic hemodialysis.

물리적 형태

Solution in phosphate buffered saline containing 0.02% sodium azide.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


시험 성적서(COA)

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문서 라이브러리 방문

P D Gorevic et al.
Proceedings of the National Academy of Sciences of the United States of America, 83(20), 7908-7912 (1986-10-01)
Systemic amyloidosis with a predilection for bone and synovium may complicate the course of patients on long-term hemodialysis. This form of amyloidosis can be typed as distinct from other amyloid diseases by using small tissue samples obtained by bone biopsy
C Bernabeu et al.
Nature, 308(5960), 642-645 (1984-04-12)
Beta 2-microglobulin (beta 2-m) is a highly conserved polypeptide (12,000 molecular weight; 12K) noncovalently associated with the heavy chain (45-48K) of the major histocompatibility complex (MHC) class I antigens. Its synthesis is required for expression of the HLA-A/B and H-2K/D
Manzoor A Wani et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(13), 5084-5089 (2006-03-22)
Two siblings, products of a consanguineous marriage, were markedly deficient in both albumin and IgG because of rapid degradation of these proteins, suggesting a lack of the neonatal Fc receptor, FcRn. FcRn is a heterodimeric receptor composed of a nonclassical

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