G0549

Corosolic acid from Lagerstroemia speciosa

≥98% (HPLC)

• 동의어(들): Corosolic acid, (2α,3β)-2,3-Dihydroxyurs-12-en-28-oic acid, 2α-Hydroxyursolic acid, Colosolic acid, Corsolic acid, Glucosol
• 실험식(Hill 표기법): C₃₀H₄₈O₄
• CAS Number: 4547-24-4
• Molecular Weight: 472.70
• MDL number: MFCD06794973
• UNSPSC 코드: 12352106
• PubChem Substance ID: 329799816
• NACRES: NA.25

속성

• Quality Level: 200
• 분석: ≥98% (HPLC)
• 양식: powder
• solubility: methanol: 1 mg/mL, clear, colorless
• 응용 분야: metabolomics; vitamins, nutraceuticals, and natural products
• 저장 온도: 2-8°C
• SMILES string: O[C@H]1[C@H](O)C(C)(C)[C@@](CC[C@]2(C)[C@]3([H])CC=C4[C@@]2(C)CC[C@]5(C(O)=O)[C@@]4([H])[C@@H](C)[C@H](C)CC5)([H])[C@]3(C)C1
• InChI: 1S/C30H48O4/c1-17-10-13-30(25(33)34)15-14-28(6)19(23(30)18(17)2)8-9-22-27(5)16-20(31)24(32)26(3,4)21(27)11-12-29(22,28)7/h8,17-18,20-24,31-32H,9-16H2,1-7H3,(H,33,34)/t17-,18+,20-,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
• InChI key: HFGSQOYIOKBQOW-ZSDYHTTISA-N

설명

일반 설명

Corosolic acid from Lagerstroemia speciosa is a pentacyclic triterpenoid found in a variety of plants, such as apples, basil, bilberries, cranberries, and prunes. It is a natural derivative of ursolic acid.

애플리케이션

Corosolic acid from Lagerstroemia speciosa has been used to study the inhibiting activity of ursolic acid and its derivative against colon cancer cells by causing degradation of β-catenins.

생화학적/생리학적 작용

Corosolic acid from Lagerstroemia speciose shows a variety of biological activities such as anti-proliferation, apoptosis, and anti-carcinogenic. It exhibits an inhibiting effect on the post-challenge plasma glucose levels in humans. Corosolic acid, due to its ability to improve glucose metabolism, has been touted to be used in the management of Type-2 Diabetes. It improves hypertension, oxidative stress, and inflammation, thereby being a potential candidate to be used against atherosclerosis-related diseases.

Triterpene phytochemical found in medicinal herbal extracts. Possesses antiatherosclerotic, antihyperlipidemic, antioxidant, antiinflammatory, antifungal, antiviral and antineoplastic activities.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable