F8307

FR-900098 monosodium salt

≥97% (NMR)

• 동의어(들): (3-(Acetylhydroxyamino)propyl)-phosphonic acid, BRN 2096083, P-[3-(Acetylhydroxyamino)propyl]-phosphonic acid
• 실험식(Hill 표기법): C₅H₁₁NNaO₅P
• CAS Number: 73226-73-0
• Molecular Weight: 219.11
• MDL number: MFCD17215926
• UNSPSC 코드: 51111800
• PubChem Substance ID: 329799770
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥97% (NMR)
• 양식: powder
• 저장 조건: desiccated; protect from light
• 색상: white to light brown
• solubility: H₂O: ≥20 mg/mL
• 저장 온도: −20°C
• SMILES string: [Na+].CC(=O)N(O)CCCP(O)([O-])=O
• InChI: 1S/C5H12NO5P.Na/c1-5(7)6(8)3-2-4-12(9,10)11;/h8H,2-4H2,1H3,(H2,9,10,11);/q;+1/p-1
• InChI key: LCFXFDGYDKNWMD-UHFFFAOYSA-M

설명

생화학적/생리학적 작용

1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative, Gram-positive bacteria, plants, and the parasite causing the most virulent form of malaria, Plasmodium falciparum (Mammals produce isoprenoids via the mevalonate pathway). Inhibiton of the enzyme provides alternative to traditional antimalaria therapy. FR-900098 is twice more effective than fosmidomycin against various strains of P. falciparum in vitro and the closely related P. vinckei in mice.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable