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Key Documents

F3133

Sigma-Aldrich

Fibroblast Growth Factor from bovine pituitary

lyophilized, suitable for cell culture

동의어(들):

FGF

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About This Item

CAS Number:
MDL number:
UNSPSC 코드:
12352202
NACRES:
NA.77

product name

Fibroblast Growth Factor from bovine pituitary, suitable for cell culture

생물학적 소스

bovine pituitary glands

Quality Level

형태

lyophilized powder

효능

1-100 ng/mL

분자량

16.4 kDa

포장

pkg of 10 and 5X10 μg

저장 조건

avoid repeated freeze/thaw cycles

기술

cell culture | mammalian: suitable

불순물

endotoxin, tested

색상

white to off-white

저장 온도

−20°C

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Fibroblast growth factors (FGF) are glycoproteins concealed in the extracellular matrix and cell surface. There are around 22 different types of FGFs known. These factors weigh in the range of 17 to 34kDa and they possess a conserved sequence of 120 amino acids.

애플리케이션

A natural mitogenic growth factor used in cell culture applications to study cell signaling and to promote fibroblast and endothelial cell growth and survival.
Fibroblast Growth Factor from bovine pituitary has been used in in vitro testicular cell culture. It has also been used as a component of myogenic culture medium.

생화학적/생리학적 작용

Fibroblast growth factors (FGF) actively participate in cellular responses including embryogenesis and organogenesis. It specifically controls cell proliferation, differentiation and migration. FGF is known to regulate nervous system functions, tissue repair mechanism and wound healing. It also controls angiogenesis of tumor cells. Abnormal FGF mediated signaling induces tumor angiogenesis, by stimulating cancer cell proliferation and survival. FGFs carries out its function by mediating through four receptor tyrosine kinases : FGF-receptors FGFR1, FGFR2, FGFR3 and FGFR4.

품질

Although the major mitogenic component of this product is FGF2, the activity per unit weight of protein is less than that of purified FGF2.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.1 mg/ml BSA.

제조 메모

Purified glands by a modification of the method of Gospodarowicz.

분석 메모

The biological activity is measured using a 3-day MTT assay.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Characterization and In Vitro Differentiation of Korean Ring-Necked Pheasant (Phasianus colchicus) Male Germ Cells
Jeong DK, et al.
Journal of Embryology transfer, 29(4), 351-359 (2014)
Modulation of osteogenic, adipogenic and myogenic differentiation of mesenchymal stem cells by submicron grooved topography
Wang PY, et al.
Journal of Materials Science. Materials in Medicine, 23(12), 3015-3028 (2012)
Cellular signaling by fibroblast growth factor receptors
Eswarakumar VP, et al.
Cytokine & Growth Factor Reviews, 16(2), 139-149 (2005)
A testis-mediated germline chimera production based on transfer of chicken testicular cells directly into heterologous testes
Lee YM, et al.
Biology of Reproduction, 75(3), 380-386 (2006)
Identification, culture, and characterization of germline stem cell-like cells in chicken testes
Jung JG, et al.
Biology of Reproduction, 76(1), 173-182 (2007)

문서

Fibroblast growth factors in cell culture and various growth factors for your research

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