E8031

Esmolol hydrochloride

≥98% (HPLC), solid

• 동의어(들): 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzenepropanoic acid methyl ester hydrochloride hydrochloride
• 실험식(Hill 표기법): C₁₆H₂₆NClO₄
• CAS Number: 81161-17-3
• Molecular Weight: 331.83
• MDL number: MFCD00941432
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329799075
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 형태: solid
• 저장 조건: desiccated
• mp: 89.0-90.6 °C
• solubility: H₂O: 12 mg/mL
• 주관자: Baxter
• 저장 온도: 2-8°C
• SMILES string: Cl.COC(=O)CCc1ccc(OCC(O)CNC(C)C)cc1
• InChI: 1S/C16H25NO4.ClH/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)20-3;/h4-5,7-8,12,14,17-18H,6,9-11H2,1-3H3;1H
• InChI key: GEKNCWBANDDJJL-UHFFFAOYSA-N
• 유전자 정보: human ... ADRB1(153) , ADRB2(154)

설명

애플리케이션

Esmolol hydrochloride (ESM) may be used as a standard in spectrophotometric and electrochemical method for the determination of ESM in biological samples and pharmaceutical formulations.

생화학적/생리학적 작용

Esmolol hydrochloride (ESM) is a class II antiarrhythmic drug. It is used to decrease the force and rate of heart contractions during surgery. Overdose of ESM can lead to side effects such as bradycardia, cardiac arrest, hypoventilation, mood disorder, and coma.

Esmolol hydrochloride is a ultrashort-acting β₁ adrenoceptor antagonist (β₁ receptor occupancy = 84.7%).

특징 및 장점

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Baxter. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves