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Merck
모든 사진(1)

주요 문서

E1636

Sigma-Aldrich

β-Estradiol 3,17-disulfate dipotassium salt

≥95%

동의어(들):

1,3,5(10)-Estratriene 3,17β-disulfate, 3,17β-Dihydroxy-1,3,5(10)-estratriene disulfate

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About This Item

Linear Formula:
C18H22O8S2K2
CAS Number:
Molecular Weight:
508.69
MDL number:
UNSPSC 코드:
51111800
PubChem Substance ID:
NACRES:
NA.77
생물학적 소스:
synthetic
양식:
powder
분석:
≥95%

생물학적 소스

synthetic

분석

≥95%

양식

powder

기술

inhibition assay: suitable

solubility

water: 50 mg/mL, clear, colorless

배송 상태

ambient

저장 온도

−20°C

SMILES string

[K].[H][C@]12CC[C@]3(C)[C@H](CC[C@@]3([H])[C@]1([H])CCc4cc(OS(O)(=O)=O)ccc24)OS(O)(=O)=O

InChI

1S/C18H24O8S2.K.H/c1-18-9-8-14-13-5-3-12(25-27(19,20)21)10-11(13)2-4-15(14)16(18)6-7-17(18)26-28(22,23)24;;/h3,5,10,14-17H,2,4,6-9H2,1H3,(H,19,20,21)(H,22,23,24);;/t14-,15-,16+,17+,18+;;/m1../s1

InChI key

CPIZVUIARARPNO-LBARCDFESA-N

생화학적/생리학적 작용

Among other effects, this conjugated estrogen selectively inhibits glutathione S-transferases.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

이미 열람한 고객

J J Barycki et al.
Archives of biochemistry and biophysics, 345(1), 16-31 (1997-09-01)
3beta-(Iodoacetoxy)dehydroisoandrosterone (3beta-IDA), an analogue of the electrophilic substrate, Delta5-androstene-3,17-dione, as well as an analogue of several other steroid inhibitors of glutathione S-transferase, was tested as an affinity label of rat liver glutathione S-transferase, isozyme 1-1. A time-dependent loss of enzyme
Angelo Quaranta et al.
PloS one, 4(11), e7699-e7699 (2009-11-06)
Dramatic declines in amphibian populations have been described all over the world since the 1980s. The evidence that the sensitivity to environmental threats is greater in amphibians than in mammals has been generally linked to the observation that amphibians are
J D Bain et al.
Steroids, 43(6), 603-619 (1984-06-01)
The efficiencies for estrogen conjugate hydrolysis were compared between enzyme hydrolysis, acid solvolysis and a new method, ammonolysis. Samples included: 1) crystalline 1,3,5(10)-estratriene-3, 17 beta-diol disulfate (estradiol 3,17-disulfate), 2) squirrel monkey urine collected following an intravenous injection of [2,4,6,7-H] 1,3,5(10)-estratriene-3,17
A H Maas et al.
Nederlands tijdschrift voor geneeskunde, 145(2), 65-69 (2001-02-28)
Coronary heart disease develops on average 10-15 years later in women than in men and is uncommon before menopause. 17 beta-estradiol has atheroprotective properties through rapid vasodilatory effects on the endothelium by stimulating nitric monoxide production and longer-term actions by
Fanfan Zhou et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 27(5), 518-523 (2005-11-01)
Human organic anion transporter 4 (hOAT4) belongs to a family of organic anion transporters which play critical roles in the body disposition of clinically important drugs, including anti-HIV therapeutics, anti-tumor drugs, antibiotics, anti-hypertensives, and anti-inflammatories. hOAT4 is expressed in the

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