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Merck
모든 사진(1)

주요 문서

D6288

Sigma-Aldrich

6α,9α-Difluoroprednisolone 21-acetate 17-butyrate

≥98%

동의어(들):

Difluprednate

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About This Item

실험식(Hill 표기법):
C27H34F2O7
CAS Number:
Molecular Weight:
508.55
EC Number:
MDL number:
UNSPSC 코드:
12352202
PubChem Substance ID:
NACRES:
NA.77

무균

non-sterile

Quality Level

분석

≥98%

형태

powder

solubility

chloroform: 50 mg/mL, clear, colorless

배송 상태

ambient

저장 온도

2-8°C

SMILES string

CCCC(=O)O[C@@]1(CC[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)COC(C)=O

InChI

1S/C27H34F2O7/c1-5-6-23(34)36-26(22(33)14-35-15(2)30)10-8-17-18-12-20(28)19-11-16(31)7-9-24(19,3)27(18,29)21(32)13-25(17,26)4/h7,9,11,17-18,20-21,32H,5-6,8,10,12-14H2,1-4H3/t17-,18-,20-,21-,24-,25-,26-,27-/m0/s1

InChI key

WYQPLTPSGFELIB-JTQPXKBDSA-N

유전자 정보

human ... NR3C1(2908)

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Atsuo Tanimoto et al.
Experimental dermatology, 27(1), 22-29 (2017-04-20)
Janus kinases (JAKs) are required for several inflammatory cytokine signalling pathways and are implicated in the pathogenesis of chronic dermatitis, including atopic dermatitis and psoriasis. JAK inhibitors are therefore promising therapeutic candidates for chronic dermatitis. In this study, we evaluated
Eric J Sigler et al.
Retina (Philadelphia, Pa.), 34(2), 237-246 (2013-07-25)
To describe the clinical and histopathologic characteristics of inflammatory deposits occurring within intermediate duration postoperative perfluoro-n-octane (PFO) for inferior retinal detachment repair. Prospective interventional case series of consecutive patients with inferior retinal detachment treated with intermediate duration postoperative vitreous cavity
Shin-ichi Yasueda et al.
Journal of pharmaceutical and biomedical analysis, 30(6), 1735-1742 (2002-12-18)
A specific and sensitive method for the determination for difluprednate (DFBA) and its metabolite (deacetylated DFBA, DFB) in aqueous humor was developed. DFBA and DFB were initially absorbed on a Pinkerton-type column, then analyzed by high-performance liquid chromatography using a
Yixuan Dong et al.
Journal of pharmaceutical sciences, 108(6), 2002-2011 (2019-01-15)
Pharmaceutical emulsions contain multiple components, such as micellar, aqueous, and oil phases, leading to complex drug transfer and equilibrium phenomena. These complex components present challenges for the bioequivalence assessment of the drug products. The objective of the study was to
Mahmoud Tawfik KhalafAllah et al.
BMJ open, 9(11), e026752-e026752 (2019-11-05)
Topical steroids are the cornerstone in controlling the inflammation after cataract surgery. Prednisolone acetate and difluprednate are the two main products for this purpose. However, it is unclear which one should be used in terms of effectiveness and safety. Systematic

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