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Merck
모든 사진(1)

Key Documents

D3439

Sigma-Aldrich

D-erythro-Dihydrosphingosine 1-phosphate

≥98% (TLC), waxy solid

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About This Item

실험식(Hill 표기법):
C18H40NO5P
CAS Number:
Molecular Weight:
381.49
MDL number:
UNSPSC 코드:
12352211
PubChem Substance ID:
NACRES:
NA.77

Quality Level

분석

≥98% (TLC)

형태

waxy solid

색상

yellow

solubility

methanol: THF: water (6:3:1): >0.5 mg/mL

저장 온도

−20°C

SMILES string

CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)COP(O)(O)=O

InChI

1S/C18H40NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h17-18,20H,2-16,19H2,1H3,(H2,21,22,23)/t17-,18+/m0/s1

InChI key

YHEDRJPUIRMZMP-ZWKOTPCHSA-N

생화학적/생리학적 작용

Negative control for sphingosine-1-phosphate.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

Van Brocklyn, J.R., et al.
The Journal of Biological Chemistry, 142, 229-229 (1998)
Sang Won Park et al.
Laboratory investigation; a journal of technical methods and pathology, 90(8), 1209-1224 (2010-05-12)
Liver failure due to ischemia and reperfusion (IR) and subsequent acute kidney injury are significant clinical problems. We showed previously that liver IR selectively reduced plasma sphinganine-1-phosphate levels without affecting sphingosine-1-phosphate (S1P) levels. Furthermore, exogenous sphinganine-1-phosphate protected against both liver
Mia Roest Laursen et al.
Metabolomics : Official journal of the Metabolomic Society, 13(6), 67-67 (2017-05-06)
Remote ischemic conditioning (RIC) is a maneuver by which short non-lethal ischemic events are applied on distant organs or limbs to reduce ischemia and reperfusion injuries caused by e.g. myocardial infarct. Although intensively investigated, the specific mechanism of this protective
Ryunosuke Ohkawa et al.
Clinical biochemistry, 48(10-11), 690-697 (2015-04-12)
Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid mediator. Although the plasma S1P concentration is reportedly determined by cellular components, including erythrocytes, platelets, and vascular endothelial cells, the possible involvement of other factors, such as serum sphingomyelin (SM) and autotaxin (ATX)

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