LC-2/ad

94072247, human lung, Epithelial

• 동의어(들): LC-2/ad Cells
• UNSPSC 코드: 41106514

속성

• 제품명: LC-2/ad, 94072247
• 생물학적 소스: human lung
• 성장 모드: Adherent
• 핵형: Modal No 53-56
• 형태학: Epithelial
• 제품: alpha-1-anti-trypsin
• 수용체: Not specified
• 기술: cell culture | mammalian: suitable
• 관련 질환(들): cancer
• 배송 상태: dry ice
• 저장 온도: −196°C

설명

세포주 기원

Human lung adenocarcinoma

세포주 설명

Established from the pleural effusion of a pulmonary adenocarcinoma in a 51 year-old Japanese female. LC-2/ad cells exhibit an epithelial appearance and a tendency to form small domes. Immunocytochemically the cells are positive for CEA and cytokeratins, including cytokeratin No.18. LC-2/ad produces at least two functionally active trypsin inhibitors together with several proteinases in vitro.

애플리케이션

LC-2/ad has been used to study the ability of RXDX-105 as a therapy for cancers which are affected by RET (proto-oncogene tyrosine-protein kinase receptor) changes.

배양 배지

RPMI 1640:HAMS F12 (1:1) + 2mM Glutamine + 10% Foetal Bovine Serum (FBS)

계대배양 정규 작업

Split confluent cultures 1:2-1:4 ie seeding at 2-5 x 10,000 cells/cm² using 0.25% trypsin or trypsin/ EDTA ; 5%CO₂; 37°C

기타 정보

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