C8221

Caffeic acid phenethyl ester

≥97% (HPLC), powder

• 동의어(들): CAPE
• 실험식(Hill 표기법): C₁₇H₁₆O₄
• CAS Number: 104594-70-9
• Molecular Weight: 284.31
• MDL number: MFCD00866470
• UNSPSC 코드: 12352108
• PubChem Substance ID: 24278341
• NACRES: NA.77

속성

• 생물학적 소스: synthetic
• Quality Level: 200
• 분석: ≥97% (HPLC)
• 양식: powder
• 저장 조건: protect from light
• 색상: off-white
• solubility: ethyl acetate: 50 mg/mL; DMSO: soluble; ethanol: soluble
• 저장 온도: −20°C
• SMILES string: Oc1ccc(\C=C\C(=O)OCCc2ccccc2)cc1O
• InChI: 1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-7+
• InChI key: SWUARLUWKZWEBQ-VQHVLOKHSA-N
• 유전자 정보: human ... NFKB2(4791)

설명

애플리케이션

Caffeic acid phenethyl ester (CAPE) has been used to determine the effect of CAPE in hyperthyroidism, as a component of culture media to measure the cytotoxicity of breast cancer cell line MDA-MB-231, to study its effects on amiodarone-induced pulmonary fibrosis in rats.

생화학적/생리학적 작용

CAPE exhibits several properties such as anticarcinogenic, immunomodulatory activities, antioxidant, antiviral, anti-inflammatory, hypoglycaemic effect, cardioprotective and inhibits gastric secretion. It also has an inhibitory effect on fibroblasts growth factor type 2 (FGF-2), a tumor growth factor in breast cancer.

Caffeic acid phenethyl ester is a specific inhibitor of the nuclear transcription factor NF-κB.

특징 및 장점

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안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves