C4238
CNS-1102
>98% (HPLC), solid
동의어(들):
Aptiganel hydrochloride, Cerestat, N-(3-Ethylphenyl)-N-methyl-N’-1-naphthalenylguanidine hydrochloride
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모든 사진(2)
About This Item
실험식(Hill 표기법):
C20H21N3 · HCl
CAS Number:
Molecular Weight:
339.86
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
Quality Level
분석
>98% (HPLC)
양식
solid
색상
white
solubility
H2O: soluble 17 mg/mL
DMSO: soluble 20 mg/mL
저장 온도
2-8°C
SMILES string
Cl[H].CCc1cccc(c1)N(C)C(=N)Nc2cccc3ccccc23
InChI
1S/C20H21N3.ClH/c1-3-15-8-6-11-17(14-15)23(2)20(21)22-19-13-7-10-16-9-4-5-12-18(16)19;/h4-14H,3H2,1-2H3,(H2,21,22);1H
InChI key
CKAKVKWRMCAYJD-UHFFFAOYSA-N
생화학적/생리학적 작용
CNS-1102 acts as a neuroprotective agent and might exhibit therapeutic effects against acute stroke and traumatic brain injury.
Noncompetitive NMDA glutamate receptor antagonist.
특징 및 장점
This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
가장 최신 버전 중 하나를 선택하세요:
K W Muir et al.
Annals of the New York Academy of Sciences, 765, 279-289 (1995-09-15)
The high affinity noncompetitive N-methyl-D-aspartate receptor antagonist CNS 1102 (aptiganel hydrochloride, Cambridge NeuroScience, Cambridge, MA.) is neuroprotective in preclinical models of stroke when administered as pretreatment or up to 60 minutes postischemia, and has potential for treatment of acute stroke
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