추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen 27 kDa
종 반응성
mouse, human, rat
기술
immunohistochemistry (frozen sections): 1:400 using frozen rat liver sections
western blot: 1:400 using a rat liver membrane preparation
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... GJB1(2705)
mouse ... Gjb1(14618)
rat ... Gjb1(29584)
일반 설명
Connexins (Cx) are a multi-gene family of highly related proteins with molecular weights ranging from 26 to 70 kDa. The structure of connexin molecules includes a cytoplasmic N-terminal region, four transmembrane domains, two extracellular loops, and a C-terminal cytoplasmic tail of varying length. The 27kD connexin protein (connexin 32, Cx32) is expressed in several tissues.
면역원
synthetic human connexin-32 peptide (amino acids 106-124).
애플리케이션
Anti-Connexin 32 (265-279) antibody produced in rabbit is suitable for immunohistochemistry (frozen sections) at a dilution of 1:400 using frozen rat liver tissue. It is also suitable for western blot at a dilution of 1:400 using a rat liver membrane preparation.
Anti-Connexin-32 (106-124) antibody produced in rabbit has been used in:
- western blotting
- immunofluorescence
- immunohistology
생화학적/생리학적 작용
Cx32 mutations is associated with X-linked Charcot-Marie-Tooth (CMTX) disease, which leads to myelin disruption and axonal degeneration.
물리적 형태
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin with 15 mM sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Transient, recurrent, white matter lesions in X-linked Charcot-Marie-Tooth disease with novel connexin 32 mutation
Hanemann CO, et al.
Archives of Neurology, 60(4), 605-609 (2003)
Connexins and their channels in cell growth and cell death
Vinken M, et al.
Cellular Signalling, 18(5), 592-600 (2006)
Hendryk Aurich et al.
Cell transplantation, 14(7), 497-506 (2005-11-16)
Although ex vivo culture of hepatocytes is known to impair functionality, it may still be considered as desirable to propagate or manipulate them in culture prior to transplantation into the host liver. The aim of this study was to clarify
Sarah Koenig et al.
Cell transplantation, 14(1), 31-40 (2005-03-26)
The mechanisms of donor hepatocyte integration into recipient liver are not fully understood. We investigated mechanisms of both the integration and interaction of transplanted hepatocytes with host liver cells as well as the repopulation of the host organ following intraportal
Cell junctions in the germinal epithelium may play an important role in spermatogenesis of the catfish P. fasciatum (Pisces, Siluriformes)
Batlouni SR, et al.
Journal of Molecular Histology, 36(1-2), 97-110 (2005)
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