C167

Cholera Toxin B subunit

solid

• 동의어(들): CTB
• MDL number: MFCD02356522
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329774903
• NACRES: NA.77

속성

• 형태: solid
• Quality Level: 200
• 분자량: ~12 kDa
• 색상: white
• 저장 온도: 2-8°C
• SMILES string: CCOc1ccccc1C(=O)Nc2ccc(Cl)c(c2)C(F)(F)F
• InChI: 1S/C16H13ClF3NO2/c1-2-23-14-6-4-3-5-11(14)15(22)21-10-7-8-13(17)12(9-10)16(18,19)20/h3-9H,2H2,1H3,(H,21,22)
• InChI key: YDXZSNHARVUYNM-UHFFFAOYSA-N

설명

일반 설명

Cholera Toxin B subunit is secreted by Vibrio cholerae. It is a pentamer and is nontoxic in nature.

애플리케이션

Cholera Toxin B subunit has been used as a tracer to study the ascending projections of the nuclei of the descending trigeminal tract (nTTD) in the zebra finch.

생화학적/생리학적 작용

Cholera Toxin B subunit stimulates both systemic and mucosal antibody production in animals and humans. CTB functions as an oral subunit vaccine for cholera, which is associated with acute watery diarrhoea.

The cholera toxin B subunit is used for track tracing in neurological research, taking advantage of GM1 ganglioside binding and retrograde transport. Tissue culture cells treated with cholera toxin are not killed and tissues of animals do not become necrotic.

주의사항

Do not freeze.

재구성

When reconstituted in 0.25 mL distilled water, the compound contains 500 μg of protein in 0.01 M sodium phosphate at pH 7.5.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable