B4750

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride

trypsin substrate

• 동의어(들): BANA, N_α-Benzoyl-DL-arginine-2-naphthylamide hydrochloride
• 실험식(Hill 표기법): C₂₃H₂₅N₅O₂ · HCl
• CAS Number: 913-04-2
• Molecular Weight: 439.94
• Beilstein: 3823291
• EC Number: 213-015-4
• MDL number: MFCD00038940
• UNSPSC 코드: 12352204
• PubChem Substance ID: 24891699
• NACRES: NA.32

속성

• 분석: ≥98% (TLC)
• 양식: powder
• solubility: DMF: 50 mg/mL, clear, colorless to faintly yellow
• 저장 온도: 2-8°C
• SMILES string: Cl[H].NC(=N)NCCCC(NC(=O)c1ccccc1)C(=O)Nc2ccc3ccccc3c2
• InChI: 1S/C23H25N5O2.ClH/c24-23(25)26-14-6-11-20(28-21(29)17-8-2-1-3-9-17)22(30)27-19-13-12-16-7-4-5-10-18(16)15-19;/h1-5,7-10,12-13,15,20H,6,11,14H2,(H,27,30)(H,28,29)(H4,24,25,26);1H
• InChI key: BNGRKDJZQIGWQF-UHFFFAOYSA-N

설명

애플리케이션

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride has been used as a substrate in the BANA test to evaluate the inhibitory activity of stefin. It has also been used as a substrate for the determination of Ki values of inhibitors toward trypsin.

생화학적/생리학적 작용

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride (BANA) helps to determine the activities of cathepsin B and papain. BANA test is also useful in identifying the number of periodontal sites with periodontal pathogens. Presence of volatile sulfur compounds (VSCs), synthesized by oral bacteria in dental plaque or tongue coating can be colorimetrically confirmed by their ability to hydrolyze N-benzoyl-DL-arginine-2-naphthylamide.

기질

A chromogenic substrate for trypsin.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)