생물학적 소스
goat
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
lyophilized powder
종 반응성
human
기술
immunohistochemistry (frozen sections): 5-15 μg/mL
neutralization: suitable
western blot: 0.1 μg/mL
UniProt 수납 번호
응용 분야
research pathology
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... BMP5(653)
면역원
recombinant human BMP-5, expressed in NSO cells.
생화학적/생리학적 작용
Bone morphogenetic proteins (BMPs) are the members of the TGF-β superfamily and are identified as the critical factors for formation of bone and cartilage. Apart from this BMPs have immune regulatory functions. The cellular effects of BMPs are mediated by a heteromeric complex composed of type I and type II receptors. BMP5 is required for the development and fine tuning of the skeletal morphology.
물리적 형태
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Cytokine & growth factor reviews, 20(5-6), 509-515 (2009-11-11)
Much evidence suggests that "developmental regulator" genes, like those encoding transcription factors and signaling molecules, are typically controlled by many modular, tissue-specific cis-regulatory elements that function during embryogenesis. These elements are often far from gene coding regions and promoters. Bone
Cytokine & growth factor reviews, 16(3), 251-263 (2005-05-06)
Bone morphogenetic proteins (BMPs), members of the transforming growth factor-beta (TGF-beta) superfamily, bind to two different serine/threonine kinase receptors, and mediate their signals through Smad-dependent and Smad-independent pathways. Receptor regulated-Smad (R-Smad) proteins specific for the BMP pathways interact with various
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