추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
fractionated antiserum
항체 생산 유형
primary antibodies
클론
polyclonal
양식
lyophilized powder
종 반응성
human
포장
vial of 2 mL lyophilized antiserum
기술
Ouchterlony double diffusion: suitable
indirect ELISA: 1:4,000-1:6,000
저장 온도
2-8°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... AMY1A(276)
일반 설명
α-amylase is primarily produced in abundance in the salivary glands and pancreas. The expression is also seen in jejunum and mammary glands. The genes encoding α-amylase are AMY1 and AMY2 located in the short arm of chromosome 1. AMY1 is responsible for producing the enzyme in saliva and mammary gland and AMY2 produces the enzyme synthesized in the pancreas. The expression of AMY1 occurs also in certain tumour tissues. Mammalian amylases are composed of three structural domains (A, B and C). Domain A contains the active site with two aspartate and one glutamate residue. Domain B borders the active site region and is essential for maintaining the protein conformation. Domain C is involved in catalytic mechanism.
특이성
The antiserum is specific for human a-amylase found in human saliva and human pancreatic extract. No reaction with other human saliva proteins or pancreatic extract proteins is observed.
면역원
human salivary α-amylase.
애플리케이션
Anti-α-Amylase antibody produced in rabbit has also been used in immunocytochemistry analysis.
Anti-a-Amylase antibody produced in rabbit has been used in immunofluorescence and immunohistochemical analysis.
Mouse pancreatic sections were fixed in 4% paraformaldehyde and used for immunohistochemistry using rabbit anti-amylase antibody at a dilution of 1:100.
생화학적/생리학적 작용
α-Amylase is essential for catalyzing the primary step in starch digestion, a main source of carbohydrate in the human diet. α-amylase hydrolysis the polysaccharide with the ultimate production of maltose, maltotriose and limit dextrins as the main products.
물리적 형태
Lyophilized from 0.01 M phosphate buffered saline, pH 7.2
재구성
Reconstitute with 2 mL deionized water.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
이미 열람한 고객
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PloS one, 12(2), e0171508-e0171508 (2017-02-23)
Lineage-selective expression of developmental genes is dependent on the interplay between activating and repressive mechanisms. Gene activation is dependent on cell-specific transcription factors that recognize transcriptional enhancer sequences. Gene repression often depends on the recruitment of Polycomb group (PcG) proteins
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Ultrastructural analysis of pancreatic acinar cells from mice fed on genetically modified soybean
Malatesta M, et al.
Journal of Anatomy, 201(5), 409-415 (2002)
Human alpha-amylase and starch digestion: An interesting marriage
Butterworth PJ, et al.
Starch/Staerke, 63(7), 395-405 (2011)
Abbas Agaimy et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(12), 1620-1626 (2011-08-16)
Acinar cell carcinoma of pancreatic type rarely occurs at extra-pancreatic sites. We report four primary liver tumors with features of pancreatic acinar cell carcinoma. The patients were two males and two females with a mean age of 65 years (range
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