A7655

Atenolol

≥98% (TLC), powder, β₁-adrenoceptor antagonist

• 동의어(들): (±)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide, 4-[2′-Hydroxy-3′-(isopropylamino)propoxy]phenylacetamide
• 실험식(Hill 표기법): C₁₄H₂₂N₂O₃
• CAS Number: 29122-68-7
• Molecular Weight: 266.34
• EC Number: 249-451-7
• MDL number: MFCD00057645
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24277748
• NACRES: NA.77

속성

• product name: Atenolol, ≥98% (TLC), powder
• Quality Level: 200
• 분석: ≥98% (TLC)
• 형태: powder
• 색상: white to off-white
• solubility: H₂O: 0.3 mg/mL; DMSO: 18 mg/mL; ethanol: 3.4 mg/mL
• 주관자: AstraZeneca
• SMILES string: CC(C)NCC(O)COc1ccc(CC(N)=O)cc1
• InChI: 1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)
• InChI key: METKIMKYRPQLGS-UHFFFAOYSA-N
• 유전자 정보: human ... ADRB1(153) ; rat ... Adrb1(24925)

설명

애플리케이션

Atenolol is a β-adrenergic blocker and used in the management of hypertension. Atenolol has antianginal and antiarrhythmic properties.

생화학적/생리학적 작용

Selective β₁-adrenoceptor antagonist; antihypertensive; antianginal; antiarrhythmic.

특징 및 장점

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

기타 정보

Shelf-life of the solid is at least three years.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)