A1472

MCA-[Asn⁶⁷⁰, Leu⁶⁷¹]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676-DNP-Lys-Arg-Arg-NH₂

≥90% (HPLC)

• 동의어(들): 7-Methoxycoumarin-4-acetyl-[Asn⁶⁷⁰, Leu⁶⁷¹]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676(2,4-dinitrophenyl)Lys-Arg-Arg amide
• 실험식(Hill 표기법): C₈₆H₁₂₅N₂₇O₂₉
• Molecular Weight: 2001.08
• MDL number: MFCD03454237
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• Quality Level: 100
• 분석: ≥90% (HPLC)
• 양식: powder
• UniProt 수납 번호: P05067
• 저장 온도: −20°C
• 유전자 정보: human ... APP(351)

설명

Amino Acid Sequence

MCA-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-DNP-Lys-Arg-Arg-NH2

애플리케이션

7-Methoxycoumarin-4-acetyl-[Asn⁶⁷⁰,Leu⁶⁷¹]-Amyloid β has been used as a fluorogenic substrate to measure β-secretase activity.

생화학적/생리학적 작용

Fluorescent peptide substrate containing the ′Swedish′ Lys-Met/Asn-Leu mutation of the amyloid presursor protein (APP) β-secretase cleavage site. May be used for assaying β-secretase-like activity of thimet oligopeptidase (TOP), EC 3.4.24.15.

Fluorescent peptide substrate with the ′Swedish′ Lys-Met/Asn-Leu mutation of amyloid presursor protein (APP) β-secretase cleavage site.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)