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Merck
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Key Documents

A0972

Sigma-Aldrich

Apolipoprotein A-II from human plasma

≥95% (SDS-PAGE), buffered aqueous solution

동의어(들):

Apo A-II

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About This Item

MDL number:
UNSPSC 코드:
12352202
NACRES:
NA.32

생물학적 소스

human plasma

Quality Level

분석

≥95% (SDS-PAGE)

형태

buffered aqueous solution

분자량

17.38 kDa

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

유전자 정보

human ... APOA2(336)

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일반 설명

Forms dimers in aqueous solutions with an association constant of 5 × 104 M-1. The association is accompanied by an enhancement of ~35% in α-helical content.

애플리케이션

Apo A-II constitutes ~20% of the protein moiety of high density lipoprotein (HDL).

생화학적/생리학적 작용

Unlike Apo A-I, Apo A-II possesses no activating properties for lectin-cholesterol acyltransferase (LCAT). Furthermore, it was found that Apo A-II inhibits the activation of LCAT by Apo A-I.

물리적 형태

Solution in 10 mM ammonium bicarbonate.

면책조항

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Effect of disulfide cleavage on the molecular weight of one of the major polypeptides of human serum high density lipoprotein.
A M. Scanu et al.
FEBS letters, 18(2), 305-307 (1971-11-01)
Cécile Voisset et al.
The Journal of biological chemistry, 280(9), 7793-7799 (2005-01-06)
The scavenger receptor class B type I (SR-BI) has recently been shown to interact with hepatitis C virus (HCV) envelope glycoprotein E2, suggesting that it might be involved at some step of HCV entry into host cells. However, due to

문서

Since cholesterol is a water-insoluble molecule it must be packaged for transport within the plasma. The particles that package cholesterol, cholesteryl esters, and triglycerides for transport, are called lipoproteins.

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