생물학적 소스
human
Quality Level
재조합
expressed in NSO cells
분석
>90% (SDS-PAGE)
형태
lyophilized powder
분자량
50-55 kDa by SDS-PAGE (reducing)
calculated mol wt ~37.3 kDa
포장
pkg of 100 μg
저장 조건
avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
기술
cell culture | mammalian: suitable
불순물
endotoxin, tested
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
human ... ACVRL1(94)
생화학적/생리학적 작용
ALK-1 is a type I complex of the serine/threonine kinases. Type I and II receptors bind ligands in the TGF-β superfamily. Human and mouse ALK-1 share approximately 71% amino acid sequence identity in their extracellular domains.
물리적 형태
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
분석 메모
Can be used as a calibrator for ALK-1 antibodies.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
A Lux et al.
The Journal of biological chemistry, 274(15), 9984-9992 (1999-04-03)
Germ line mutations in one of two distinct genes, endoglin or ALK-1, cause hereditary hemorrhagic telangiectasia (HHT), an autosomal dominant disorder of localized angiodysplasia. Both genes encode endothelial cell receptors for the transforming growth factor beta (TGF-beta) ligand superfamily. Endoglin
P ten Dijke et al.
Oncogene, 8(10), 2879-2887 (1993-10-01)
Human cDNA clones encoding four novel putative transmembrane protein serine/threonine kinases, denoted activin receptor-like kinase (ALK) -1, -2, -3 and -4, were obtained using a polymerase chain reaction (PCR)-based strategy. The PCR primers were designed based upon the sequence similarity
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