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Merck
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Key Documents

88417

Sigma-Aldrich

MTT Formazan

MTT reduction end product, powder

동의어(들):

1-(4,5-Dimethylthiazol-2-yl)-3,5-diphenylformazan, Thiazolyl blue formazan

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About This Item

실험식(Hill 표기법):
C18H17N5S
CAS Number:
Molecular Weight:
335.43
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.83

product name

MTT Formazan, MTT reduction end product

Quality Level

형태

powder

solubility

chloroform: 10 mg/mL, clear, dark violet

SMILES string

Cc1nc(\N=N\C(=N\Nc2ccccc2)c3ccccc3)sc1C

InChI

1S/C18H17N5S/c1-13-14(2)24-18(19-13)23-22-17(15-9-5-3-6-10-15)21-20-16-11-7-4-8-12-16/h3-12,20H,1-2H3/b21-17+,23-22+

InChI key

GIFKVQOPAJDJLO-SZVLODPRSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

MTT Formazan has been used in cell viability assay.

생화학적/생리학적 작용

MTT assay is a colorimetric reaction, generally used to examine cell viability. It involves the enzymatic reduction of a yellow-colored, water-soluble, 3-[4,5-dimethylthiazole-2-yl]-2,5-diphenyltetrazolium bromide (MTT) to purple-colored, water-insoluble, MTT-formazan. This reaction is catalyzed by mitochondrial dehydrogenase and only occurs in viable cells. Thus, the amount of blue formazan is proportional to the number of viable cells. The absorbance of the formazan solution is analyzed spectrophotometrically at 570 nm.

기타 정보

Reviews: Tetrazolium salts and formazans

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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