74817

FITC-CM-Dextran

average mol wt 150,000

• 동의어(들): FITC-CM-Dextran 150, Fluorescein isothiocyanate–Carboxymethyl–Dextran
• UNSPSC 코드: 12352108
• NACRES: NA.32

속성

• 생물학적 소스: synthetic
• Quality Level: 100
• 결합: FITC conjugate
• 양식: powder or crystals
• 분자량: average mol wt 150,000
• 구성: carboxymethyl content, 3-7%
• 라벨링 범위: 0.001-0.020 mol FITCmol glucose
• 형광: λ_ex 493 nm; λ_em 517 nm±5 nm in 0.1 M Tris pH 8.0

설명

일반 설명

FITC-CM-Dextran, also known as Fluorescein isothiocyanate–Carboxymethyl–Dextran, is an anionic fluorescent probe. The carboxyl group provides the negative charge, which improves the overall permeability of the molecule. It is supplied as a yellow powder that is freely soluble in water and electrolyte solutions. FITC-CM-Dextran is insoluble in most organic samples such as ethanol, methanol, acetone, and chloroform.

FITC-CM-Dextran is manufactured by reacting selected dextran fractions with an activated carboxymethyl derivative in alkali, whereby O-carboxymethyl groups are introduced along the dextran chain.

애플리케이션

FITC-CM-dextran is used to study drug intake and delivery mechanisms in HeLa cell lines. FITC-CM-Dextran was chosen due to its high water solubility and negative charge.

It is also a suitable molecule to be used in encapsulation studies for polymersomal drug delivery systems or Ps DDS . FITC-CM-Dextran is a biocompatible molecule used as a starting material in several pharmaceutical and diagnostic applications.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable