356M-1

Cytokeratin 5 & 6 (D5 & 16B4) Mouse Monoclonal Antibody

• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100; 500
• 결합: unconjugated
• 항체 형태: culture supernatant
• 항체 생산 유형: primary antibodies
• 클론: D5 & 16B4, monoclonal
• 설명: For In Vitro Diagnostic Use in Select Regions (See Chart)
• 양식: buffered aqueous solution
• 종 반응성: human
• 포장: vial of 0.1 mL concentrate (356M-14); vial of 0.5 mL concentrate (356M-15); bottle of 1.0 mL predilute (356M-17); vial of 1.0 mL concentrate (356M-16); bottle of 7.0 mL predilute (356M-18)
• 제조업체/상표: Cell Marque^™
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
• 동형: IgG1
• 제어: mesothelioma
• 배송 상태: wet ice
• 저장 온도: 2-8°C
• 시각화: cytoplasmic
• 유전자 정보: human ... KRT5(3852)

설명

일반 설명

Anti-CK 5 & 6 positivity is seen in 65% to 100% of epithelioid mesotheliomas, in 0% to 19% of lung adenocarcinomas, and in 22% to 80% of serous carcinoma of the ovary and peritoneum. Keratin 5 & 6 expression in lung adenocarcinoma is not common, and when it occurs, the reaction is usually confined to small focal areas or scattered cells. The most probable cause of this finding is the presence of squamous differentiation of lung adenocarcinoma. Anti-CK 5 & 6 positivity has been useful in recognizing squamous cell carcinoma of the skin. Less than 10% of carcinomas of the breast, colon, and prostate stain positively for this marker. Anti-CK 5 & 6 has also been used successfully as a myoepithelial cell marker in the prostate and breast to determine malignancy. Anti-CK 5 & 6 is a useful marker to distinguish lung squamous cell carcinoma from lung adenocarcinoma and large cell carcinoma within a panel including antibodies against TTF-1, Napsin A, p63, SOX-2, desmocollin3, and desmoglein3.

품질

IVD

IVD

IVD

RUO

결합

Cytokeratin 5 & 6 Positive Control Slides, Product No. 356S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

제조 메모

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

기타 정보

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법적 정보

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