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Merck
모든 사진(1)

주요 문서

31390

Sigma-Aldrich

Dextran from Leuconostoc spp.

Mr ~70,000

동의어(들):

DEXTRAN 70

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About This Item

Linear Formula:
(C6H10O5)n
CAS Number:
EC Number:
MDL number:
UNSPSC 코드:
12352201
NACRES:
NA.25

생물학적 소스

(Leuconostoc spp)

양식

powder

분자량

Mr ~70,000

손실

≤7% loss on drying

색상

white

mp

483  °C ((901 °F ))

solubility

water: 0.75 g/5mL, clear

흡수

≤0.05 at 375 nm in H2O at 10%

저장 온도

room temp

SMILES string

O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O

InChI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

InChI key

FZWBNHMXJMCXLU-UHFFFAOYSA-N

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일반 설명

Dextran is an extracellular bacterial polymer of D-glucopyranose. It primarily consists of α-(1→6) linkage in the main chain and a variable amount of α-(1→2), α-(1→3), α-(1→4) branched linkages.

애플리케이션

Dextran from Leuconostoc spp. has been used:
  • for the isolation of islets from pancreatic tissue by centrifugation
  • as a component of Earle′s bicarbonate buffer for placental perfusion
  • for the isolation of rat brain microvessels

생화학적/생리학적 작용

Dextran is a, which is commercially used as a drug, particularly as a blood plasma volume expander. It is used as an adjuvant, emulsifier, carrier, and stabilizer in the food, pharmaceutical, and chemical industries. Sephadex, a cross-linked dextran is broadly used for the separation and purification of protein. In the food industry, dextran found its use as a thickener for jam and ice cream. It inhibits the crystallization of sugar, thereby enhancing moisture retention. This helps in maintaining the flavor and appearance of various food items.

기타 정보

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.
Enhances immunoprecipitation sensitivity

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

M F Dumon et al.
Electrophoresis, 11(10), 846-851 (1990-10-01)
A modification of crossed immunoelectrophoresis for the analysis of plasma lipoproteins is described and is called polyacrylamide gel-crossed immunoelectrophoresis. The incorporation of albumin in the first-dimensional gel facilitates the transfer of the larger lipoproteins containing apolipoprotein B from the first-dimensional
Sin-Yu Yang et al.
Transplantation proceedings, 51(5), 1458-1462 (2019-06-04)
Subcutaneous pockets provide an extrahepatic transplant site for islet grafting to treat type 1 diabetes. However, a hypoxic environment may cause central necrosis to islets and lead to graft failure. Our previous studies focused on a pre-treated subcutaneous site with
Kai-Chiang Yang et al.
Biotechnology and bioengineering, 115(9), 2341-2355 (2018-05-20)
Transplantation of encapsulated porcine islets is proposed to treat type 1 diabetes. However, the envelopment of fibrous tissue and the infiltration of immune cells impair islet function and eventually cause implant failure. It is known that hemodialysis using an ethylene
W Michael Babinchak et al.
Nature communications, 11(1), 5574-5574 (2020-11-06)
Liquid-liquid phase separation (LLPS) of proteins that leads to formation of membrane-less organelles is critical to many biochemical processes in the cell. However, dysregulated LLPS can also facilitate aberrant phase transitions and lead to protein aggregation and disease. Accordingly, there
Diego Delgado et al.
Human gene therapy, 23(4), 345-355 (2012-02-03)
The goal of the present study was to analyze the potential application of nonviral vectors based on solid lipid nanoparticles (SLN) for the treatment of ocular diseases by gene therapy, specifically X-linked juvenile retinoschisis (XLRS). Vectors were prepared with SLN

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