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Merck
모든 사진(1)

주요 문서

301M-1

Sigma-Aldrich

Cytokeratin, LMW (AE1) Mouse Monoclonal Antibody

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41
클론:
AE1, monoclonal
application:
IHC (p)
종 반응성:
human
기술:
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
citations:
9

생물학적 소스

mouse

Quality Level

100
500

결합

unconjugated

항체 형태

culture supernatant

항체 생산 유형

primary antibodies

클론

AE1, monoclonal

설명

For In Vitro Diagnostic Use in Select Regions (See Chart)

양식

buffered aqueous solution

종 반응성

human

포장

vial of 0.1 mL concentrate (301M-14)
vial of 0.5 mL concentrate (301M-15)
bottle of 1.0 mL predilute (301M-17)
vial of 1.0 mL concentrate (301M-16)
bottle of 7.0 mL predilute (301M-18)

제조업체/상표

Cell Marque

기술

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

동형

IgG1κ

제어

prostate

배송 상태

wet ice

저장 온도

2-8°C

시각화

cytoplasmic

유전자 정보

human ... KRT1(3848)

일반 설명

Anti-cytokeratin, low molecular weight (AE1) labels most acidic keratins; therefore, it is a broadly reactive antibody staining most epithelia and their neoplasms. Members of the acidic and basic cytokeratin subfamilies are found together in pairs; each epithelium contains at least one acidic and one basic keratin so this antibody can show the distribution of keratin containing cells in epithelia. This antibody has shown great sensitivity and broad specificity for keratins under various conditions of fixation and staining. Anti-low molecular weight cytokeratin (AE1) is particularly suited to distinguish poorly differentiated carcinomas from non-epithelial neoplasms. This marker stains both normal and neoplastic cells of epithelial origin.

품질


IVD

IVD

IVD

RUO

결합

Cytokeratin, LMW Positive Control Slides, Product No. 301S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

제조 메모

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

기타 정보

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

법적 정보

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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문서 라이브러리 방문

A R Judkins et al.
American journal of clinical pathology, 110(5), 641-646 (1998-11-05)
Immunohistochemistry occasionally is used to determine the lineage of entirely necrotic tumors. However, the sensitivity and specificity of antibodies on necrotic tissue are unknown. To determine the usefulness of immunohistochemistry with necrotic lesions, a series of 24 known tumors consisting
R Kitazawa et al.
Virchows Archiv : an international journal of pathology, 435(2), 137-142 (1999-12-22)
A 69-year-old man had a hepatic tumour occupying the left and half of the right lobe, with portal vein thrombus. There were hypercalcaemia and hypophosphataemia with increased nephrogenous cyclic adenosine monophosphate; bone metastases were excluded. Serum parathyroid hormone-related protein (PTHrP)
A J Demetris et al.
The American journal of pathology, 149(2), 439-448 (1996-08-01)
The ductular reaction to acute submassive necrosis was studied in human livers removed at the time of orthotopic liver transplantation. Single, double, and triple immunohistochemical labeling in combination with morphometry was used to analyze the phenotype and proliferative and apoptotic
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 166-174 (2002)
V Eusebi et al.
The American journal of surgical pathology, 14(8), 737-747 (1990-08-01)
We present four cases of a malignant thyroid tumor showing morphologic, immunocytochemical, and ultrastructural features of endothelial cell differentiation. The tumor cells had epithelioid features and displayed strong immunoreactivity for keratin. There was no evidence of follicular or C-cell differentiation

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