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Merck
모든 사진(2)

주요 문서

3010-05A

Sigma-Aldrich

Human Subclavian Artery Endothelial Cells: HScAEC, adult

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About This Item

UNSPSC 코드:
41106514
NACRES:
NA.81

생물학적 소스

human subclavian artery (normal)

Quality Level

포장

pkg of 500,000 cells

제조업체/상표

Cell Applications, Inc

성장 모드

Adherent

핵형

2n = 46

형태학

Endothelial

기술

cell culture | mammalian: suitable

관련 질환(들)

bipolar disorder; cardiovascular diseases; cancer

배송 상태

dry ice

저장 온도

−196°C

일반 설명

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.

HScAEC, along with human aortic (HAOEC), carotid artery (HCtAEC), coronary artery (HCAEC) and brachiocephalic artery (HBcAEC) have been used to demonstrate that not only blood vessels from different tissues are highly heterogeneous, they also interact differently with leukocytes during the inflammation response (Scott, 2013). The authors further showed that differential N-glycosylation of commonly expressed vascular adhesion molecules may be responsible for this heterogeneity, as well as for modulation of signaling under resting and activated inflammatory conditions. This also explains why specific vascular beds may be more or less susceptible to particular diseases or stimuli. Importantly, if cells from different sources were used, these results could not be convincingly validated due to a number of uncontrolled variables, such as age, race, genetic variability or life style choices of the donors.

Because of the complex heterogeneity that exists not only between different donors, but even between different vascular beds in the same individual, it would be prudent to confirm any new findings on primary cell lots coming from several different origins.

세포주 기원

Artery

애플리케이션

blood pressure, blood supply, tissue oxygenation

성분

Basal Medium containing 10% FBS & 10% DMSO

제조 메모

  • 2nd passage, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 10 doublings

계대배양 정규 작업

Please refer to the HScAEC Culture Protocol.

면책조항

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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