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Merck
모든 사진(1)

문서

30058

Sigma-Aldrich

Lipase Substrate

≥95% (HPLC)

동의어(들):

1,2-Di-O-lauryl-rac-glycero-3-(glutaric acid 6-methylresorufin ester)

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About This Item

실험식(Hill 표기법):
C45H69NO8
CAS Number:
Molecular Weight:
752.03
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.83

분석

≥95% (HPLC)

형태

powder

solubility

ethanol: soluble (10mg/mL)

형광

λex 529 nm; λem 600 nm in 0.1 M Tris pH 8.4

저장 온도

2-8°C

SMILES string

CCCCCCCCCCCCOCC(COC(=O)CCCC(=O)Oc1ccc2N=C3C=CC(=O)C(C)=C3Oc2c1)OCCCCCCCCCCCC

InChI

1S/C45H69NO8/c1-4-6-8-10-12-14-16-18-20-22-31-50-34-38(51-32-23-21-19-17-15-13-11-9-7-5-2)35-52-43(48)25-24-26-44(49)53-37-27-28-39-42(33-37)54-45-36(3)41(47)30-29-40(45)46-39/h27-30,33,38H,4-26,31-32,34-35H2,1-3H3

InChI key

FYOMYGYHAZESGQ-UHFFFAOYSA-N

일반 설명

Lipase substrate (1,2-Di-O-lauryl-rac-glycero-3-(glutaric,acid 6-methylresorufin) ester, DGGR) is a chromogenic substrate for lipases. It is used in colorimetric methods to measure lipase activity. This substrate produces a red-purple compound, methylresorufin, upon digestion by the lipase enzyme.

애플리케이션

Lipase Substrate is used as substrate in a high‑throughput screening assay to measure the lipase activity in response to lipstatin production

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

Ievgeniia Ostrov et al.
Food microbiology, 82, 316-324 (2019-04-28)
Biofilm-forming Bacillus species are often involved in contamination of dairy products and therefore present a major microbiological challenge in the field of food quality and safety. In this study, we sequenced and analyzed the genomes of milk- and non-milk-derived Bacillus
Sébastien Cadau et al.
International journal of molecular sciences, 23(21) (2022-11-12)
Atopic dermatitis (AD), the most common inflammatory skin disorder, is a multifactorial disease characterized by a genetic predisposition, epidermal barrier disruption, a strong T helper (Th) type 2 immune reaction to environmental antigens and an altered cutaneous microbiome. Microbial dysbiosis
Michal Híreš et al.
Current microbiology, 75(5), 580-587 (2017-12-20)
Pancreatic lipase inhibitors, such as tetrahydrolipstatin (orlistat), are used in anti-obesity treatments. Orlistat is the only anti-obesity drug approved by the European Medicines Agency (EMA). The drug is synthesized by saturation of lipstatin, a β-lactone compound, isolated from Streptomyces toxytricini
Marie-Aude Robert de Rancher et al.
Scandinavian journal of clinical and laboratory investigation, 79(8), 572-578 (2019-10-01)
Non-linearity within the primary measurement range of a lipase assay (<300 U/L) has been shown on Cobas® Roche analyzers, causing gaps in results distribution between 300 and 400 U/L. Since, new lipase method applications (LMAs) have been used. The purpose is to
Yan Q Chen et al.
Journal of lipid research, 61(8), 1203-1220 (2020-06-04)
Angiopoietin-like protein (ANGPTL)8 has been implicated in metabolic syndrome and reported to regulate adipose FA uptake through unknown mechanisms. Here, we studied how complex formation of ANGPTL8 with ANGPTL3 or ANGPTL4 varies with feeding to regulate LPL. In human serum

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