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Merck
모든 사진(1)

주요 문서

27597

Sigma-Aldrich

Coenzyme Q9

≥96.0% (HPLC)

동의어(들):

Q-9, Ubiquinone-45, Ubiquinone-9

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About This Item

실험식(Hill 표기법):
C54H82O4
CAS Number:
Molecular Weight:
795.23
Beilstein:
1900081
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.51

Quality Level

분석

≥96.0% (HPLC)

양식

powder

응용 분야

cell analysis

저장 온도

−20°C

SMILES string

COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(\C)C)=C(C)C1=O

InChI

1S/C54H82O4/c1-40(2)22-14-23-41(3)24-15-25-42(4)26-16-27-43(5)28-17-29-44(6)30-18-31-45(7)32-19-33-46(8)34-20-35-47(9)36-21-37-48(10)38-39-50-49(11)51(55)53(57-12)54(58-13)52(50)56/h22,24,26,28,30,32,34,36,38H,14-21,23,25,27,29,31,33,35,37,39H2,1-13H3/b41-24+,42-26+,43-28+,44-30+,45-32+,46-34+,47-36+,48-38+

InChI key

UUGXJSBPSRROMU-WJNLUYJISA-N

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일반 설명

Coenzyme Q9 (Ubiquinone-9; Ubi-9) is a 9 isoprenyl group member of a family of ubiquinones that share a quinine chemical group but differ in the number of isoprenyl chemical subunits in their tail. The CoQ compounds are lipid soluble components of cell membranes.

애플리케이션

Coenzyme Q9 (Ubiquinone-9; Ubi-9) may be used in the study of ubiquinones in vivo and in vitro. Coenzyme Q9 may be used as a reference compound in analytic procedures that monitor specific ubiquinone levels under various physiological and pathological conditions and in food-stocks.
Coenzyme Q9 has been used to investigate its interference in the detection of coenzyme Q10 (CoQ10) by fluorescent spectrophotometer (FS-ECA). It has also been used as an analyte in chromatographic analysis of different biological samples that correspond to different genetic conditions.

생화학적/생리학적 작용

The coenzyme Q (CoQ) can perform multiple functions such as electron and proton transport. CoQ9 performs similar functions to CoQ10 as the native CoQ in Caenorhabditis elegans. CoQ9 as well as other CoQ molecules may have an impact on cell life-span and these molecules are seeing increase usage in such studies.

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

기타 정보

An efficient electron and proton translocator in liposome systems; Prevents the appearance of adriamycin®-associated cardiotoxic phenomena in mice and rabbits.

법적 정보

Adriamycin is a registered trademark of RDF Pharmacia & Upjohn S.P.A.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

G. Hauska
Dev. Bioenerg. Biomembr., 1, 177-177 (1977)
A rapid and non-invasive fluorescence method for quantifying coenzyme Q10 in blood and urine in clinical analysis
Fei X, et al.
Journal of Clinical Laboratory Analysis, e23130-e23130 (2019)
Lidiya Bebrevska et al.
Journal of ethnopharmacology, 127(1), 112-117 (2009-10-06)
Oxidative stress has been associated with many pathological disorders such as atherosclerosis, diabetes and cancer. Supplementation with exogenous antioxidants, including phenolic compounds from plant sources, may help to restore the pro-oxidative/antioxidative balance. To take into account effects of absorption, metabolisation
Rohit Kohli et al.
Hepatology (Baltimore, Md.), 52(3), 934-944 (2010-07-08)
Diets high in saturated fat and fructose have been implicated in the development of obesity and nonalcoholic steatohepatitis (NASH) in humans. We hypothesized that mice exposed to a similar diet would develop NASH with fibrosis associated with increased hepatic oxidative
Adriamycin associated cardiotoxicity: research on prevention with coenzyme Q.
C Bertazzoli et al.
Pharmacological research communications, 9(3), 235-250 (1977-03-01)

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